Prevention of periodontal inflammation in microgravity modeling

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THE PURPOSE

Of the study was to assess oral microbiocenosis changes in participants of microgravity modeling in a control group and using prophylaxis in the form of a probiotic supplement with 1.0·10⁹CFU of Streptococcus salivarius strain in one lozenge and a dairy product containing not less than 1·10⁷ CFU of Streptococcus salivarius subsp. thermophilus strain in one gram.

MATERIALS AND METHODS

The study included 15 participants aged 25—40 years from the “Dry Immersion-2018” experiment. Five participants were included in the control group, while 10 participants were divided into 3 prophylactic groups: group I with 3 people (1 glass of dairy after evening teethbrushing and 1 glass of dairy after breakfast and teethbrushing). Group II with 3 people dissolving 1 probiotic lozenge at bedtime after teethbrushing and 1 lozenge after breakfast and teethbrushing. Group III with 4 people tested the synergism of protective streptococcus strains according to the scheme: 1 glass of dairy before nightsleep after teethbrushing and 2 probiotic lozenges under the tongue during the day. Changes were assessed by the dynamics of the Eubiotic Index and the Community Periodontal Index of Treatment Need (CPITN).

RESULTS

A significant deterioration of the periodontal condition was recorded in the control group: a growth of supragingival and subgingival tartar, bleeding gums, and a growth of pathogenic microflora. In all three prophylactic groups, a positive shift was detected in Eubiotic Index. In groups I and II there were no changes on CPITN index scale, and in group III an improvement in periodontal condition was recorded.

CONCLUSION

The probiotic drug showed a positive prophylactic effect and found synergy with the dairy product based on the Streptococcus salivarius subsp. thermophilus strain.

Keywords:

microgravity

prophylaxis

periodontitis

oral cavity

Authors:

Prokopovich L.S.

Institute of Biomedical Problems of the Russian Academy of Sciences

ORCID: 0000-0002-3699-4962

Ilyin V.K.

Institute of Biomedical Problems of the Russian Academy of Sciences

ORCID: 0000-0003-3896-5003

Drobyshev A.Y.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

ORCID: 0000-0002-1710-6923

Received:

12.05.2023

Accepted:

07.07.2023

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