Pregnancy when accompanied by oncopathology is a topic of grave concern for modern obstetrics. Annually, from 17 to 38 new cases per 100.000 births are registered. The question of whether to continue a pregnancy is determined individually, and depends on the duration of gestation, the prevalence of the cancer, and the wishes of the patient. In the first trimester, it is recommended to terminate the pregnancy and perform standard all-inclusive therapy. From the second trimester onwards, therapeutic measures include surgical and medical treatment. Chemotherapy is possible and relatively safe after the end of the embryogenesis period. The regimens and doses of the drugs used are identical to those developed for non-pregnant patients. The last course of chemotherapy should be completed no later than 3 weeks before delivery. The article presents information on the specifics of the action of chemotherapy and the risks of its use in pregnancy.