The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Iashchuk A.G.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Maslennikov A.V.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Dautova L.A.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Fatkullina I.B.

Department of Obstetrics and Gynecology with Course of the Institute of Additional Professional Education, Bashkir State Medical University, Ministry of Health of Russia, Ufa, Russia

Popova E.M.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Gazizova G.Kh.

Department of Obstetrics and Gynecology with Course of the Institute of Additional Professional Education, Bashkir State Medical University, Ministry of Health of Russia, Ufa, Russia

Sakaev R.I.

Department of Obstetrics and Gynecology with Course of the Institute of Additional Professional Education, Bashkir State Medical University, Ministry of Health of Russia, Ufa, Russia

A differentiated approach to managing patients with the thin endometrium

Authors:

Iashchuk A.G., Maslennikov A.V., Dautova L.A., Fatkullina I.B., Popova E.M., Gazizova G.Kh., Sakaev R.I.

More about the authors

Journal: Russian Bulletin of Obstetrician-Gynecologist. 2019;19(2): 52‑56

DOI: 10.17116/rosakush20191902152

Views: 2699

Downloaded: 86

Download PDF (RU)
Contact the author
Table of contents

A DIFFERENTIATED APPROACH TO MANAGING PATIENTS WITH THE THIN ENDOMETRIUM
A DIFFERENTIATED APPROACH TO MANAGING PATIENTS WITH THE THIN ENDOMETRIUM

To cite this article:

Iashchuk AG, Maslennikov AV, Dautova LA, Fatkullina IB, Popova EM, Gazizova GKh, Sakaev RI. A differentiated approach to managing patients with the thin endometrium. Russian Bulletin of Obstetrician-Gynecologist. 2019;19(2):52‑56. (In Russ.)
https://doi.org/10.17116/rosakush20191902152

 
 
Подписка 2025-2 (Russian Bulletin of Obstetrician-Gynecologist)
 
МСФ на ЯМ
Close metadata
Recommended articles:
Expe­rience of combined treatment of patients with infe­rtility operated for exte­rnal geni­tal endo­metriosis. Russian Bulletin of Obstetrician-Gynecologist. 2024;(3):77-81
Predicting the risk of decreased ovarian rese­rve after surgical treatment of patients with deep infi­ltrative endo­metriosis using arti­ficial inte­lligence. Russian Bulletin of Obstetrician-Gynecologist. 2024;(3):92-102
Correlation depe­ndence of tissue inhi­bitor of meta­lloproteinase-1 levels and follicular fluid morphology in patients with combined (uterine myoma and endo­metriosis) infe­rtility in the ART-programs. Russian Bulletin of Obstetrician-Gynecologist. 2024;(4):21-28
Significance of cell therapy in treatment of patients with thin endo­metrium and Ashe­rman’s syndrome. Russian Bulletin of Obstetrician-Gynecologist. 2024;(5):42-48
Predictors of success of in vitro fertilization with cryotransfer in patients with chro­nic endo­metritis acco­rding to laser conversion testing. Russian Journal of Human Reproduction. 2024;(2):62-73
The dile­mma of mana­gement of patients with endo­metrioma and infe­rtility. Russian Journal of Human Reproduction. 2024;(4):29-37
An inte­grated approach to endo­metrial examination in case of repeated failures in ART cycles: a pilot study. Russian Journal of Human Reproduction. 2024;(4):51-58
The influence of embryo culture technologies using traditional and TLT incu­bators on reproductive outcomes in women with different prognoses for the success of in vitro fertilization. Russian Journal of Human Reproduction. 2024;(4):71-77
Local cyto­kine profile of the endo­metrium in patients with repeated implantation failures and its pharmacological correction by the secretome of peri­pheral blood mono­nuclear cells. Russian Journal of Human Reproduction. 2024;(5):46-54
Clinical and anamnestic features of patients with recu­rrence of deep infi­ltrative endo­metriosis. Russian Journal of Human Reproduction. 2024;(5):89-100

One of the causes of infertility may be the thin endometrium. However, the latter is characteristic of two fundamentally different conditions: the atrophic variant of chronic endometritis and endometrial regenerative-plastic insufficiency. This review presents the principles of a differentiated approach to managing patients with the above mentioned syndrome

Keywords:

thin endometrium
endometrial regenerative-plastic insufficiency
chronic endometritis
infertility

Authors:

Iashchuk A.G.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Maslennikov A.V.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Dautova L.A.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Fatkullina I.B.

Department of Obstetrics and Gynecology with Course of the Institute of Additional Professional Education, Bashkir State Medical University, Ministry of Health of Russia, Ufa, Russia

Popova E.M.

Kafedra akusherstva i ginekologii #2 Bashkirskogo gosudarstvennogo meditsinskogo universiteta, Ufa

Gazizova G.Kh.

Department of Obstetrics and Gynecology with Course of the Institute of Additional Professional Education, Bashkir State Medical University, Ministry of Health of Russia, Ufa, Russia

Sakaev R.I.

Department of Obstetrics and Gynecology with Course of the Institute of Additional Professional Education, Bashkir State Medical University, Ministry of Health of Russia, Ufa, Russia

List of references:

  1. El-Toukhy T, Coomarasamy A, Khairy M, Sunkara K, Seed P, Khalaf Y, Braude P. The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles. Fertility and Sterility. 2008;89:832-839. https://doi.org/10.1016/j.fertnstert.2007.04.031
  2. Kumbak B, Erden HF, Tosun S, Akbas H, Ulug U, Bahceci M. Outcome of assisted reproduction treatment in patients with endometrial thickness less than 7 mm. Reprod Biomed Online. 2009;18:79-84. https://doi.org/10.1016/s1472-6483(10)60428-2
  3. Marinkin IO, Kuleshov VM, Ilizarova NA, Aidagulova SV. New interpretation of endometrial receptivity reduction in recurrent miscarriage. Status Praesens. 2013:6:23:74-80. (In Russ.)
  4. Kellet EP, Shurshalina AV, Korneeva IE. The role of the endometrium in the failure of the implementation of reproductive function. Problemy reproduktsii. 2010;2:16-20. (In Russ.)
  5. Cicinelli E, Matteo M, Tinelli R, Pinto V, Marinaccio M, Indraccolo U, De Ziegler D, Resta L. Chronic endometritis due to common bacteria is prevalent in women with recurrent miscarriage as confirmed by improved pregnancy outcome after antibiotic treatment. Reprod Sci. 2014;21:5:640-647. https://doi.org/10.1177/1933719113508817
  6. Proshin SN, Glushakov RI, Semenova IV, Vorobtsova IN, Saikovskaya LA, Tapil’skaya NI. Clinical and immunological efficiency of sodium nucleospermate in treating chronic endometritis and infertility complicated by HPV infection. Eksp Klin Farmakol. 2013;76: 3:27-30. (In Russ.)
  7. Radzinskiy VE. Undeveloped pregnancy. Metodicheskie rekomendatsii MARS (Mezhdistsiplinarnoi assotsiatsii spetsialistov reproduktivnoi meditsiny). Moscow: Redaktsiya zhurnala Status Praesens. 2015;48. (In Russ.)
  8. Obstetrics: National guide. Eds. Ailamazyan EK, Kulakov VI, Radzinskiy VE, Savel´ev G.M. Moscow: GEOTAR-Media, 2014;1200. (In Russ.)
  9. Volkova EYu, Silant’eva ES. Pregravid preparation for chronic endometritis. Effektivnaya farmakoterapiya. 2014;32:36-39. (In Russ.)
  10. Isaacs Jr JD, Wells CS, Williams DB, Odem RR, Gast MJ, Strick RC. Endometrial thickness is a valid monitoring parameter in cycles of ovulation induction with metropins alone. Fertil Steril. 1996;65:262-266. https://doi.org/10.1016/s0015-0282(16)58082-0
  11. Weissman A, Gotlieb L, Casper RF. The detrimental effect of increased endometrial thickness on implantation and pregnancy rates and outcome in in vitro fertilization program. Fertil Steril. 1999;71:147-149. https://doi.org/10.1016/s0015-0282(98)00413-0
  12. Alfer J, Happel L, Dittrich R, Beckmann MW, Hartmann A, Gaumann A, Buck VU, Classen-Linke I. Insufficient angiogenesis: cause of abnormally thin endometrium in subfertile patients? Geburtshilfe Frauenheilkd. 2017;77:7:756-764. https://doi.org/10.1055/s-0043-111899
  13. Abdullaev RYa, Grabar’ VV, Lysenko TP, Safonova IN, Dedzho VD. Dopplerography in gynecology. Kharkov: Novoe slovo. 2009;104. (In Russ.)
  14. Smith SK. Angiogenesis and implantation. Hum Reprod. 2000; 15:6:59-66.
  15. Plyasunova MP, Hlybova SV. Chronic endometritis as one of the actual problems in modern gynecology. Vyatskii meditsinskiy vestnik. 2013;1:44-53. (In Russ.)
  16. Chertovskikh MN. The value of hysteroscopy in preparing the endometrium for the implementation of the programs of auxiliary reproductive technologies. Lechenie i profilaktika. 2013;2:6:59-63. (In Russ.)
  17. Makarov OV, Khashukoeva AZ, Svitich OA, Markova EA, Khlynova SA. Antiviral photodynamic therapy: a new look at the treatment of recurrent miscarriage associated with chronic mixed viral infection. Akusherstvo i ginekologiya. 2013;6:11-13. (In Russ.)
  18. Zhang T, Huang C, Du Y, Lian R, Mo M, Zeng Y, & Mor G. Successful treatment with intrauterine delivery of dexamethasone for repeated implantation failure. American Journal of Reproductive Immunology. 2017;78:6:e12766. https://doi.org/10.1111/aji.12766
  19. Zarochentseva NV, Arshakyan AK, Men’shikova NS, Titchenko YuT. Chronic endometritis: etiology, clinical presentation, diagnosis, treatment. Rossiiskii vestnik akushera-ginekologa. 2013;5:21-27. (In Russ.)
  20. Christiansen OB, Larsen EC, Egerup P. Intravenous immunoglobulin treatment for secondary recurrent miscarriage: a randomised, double-blind, placebo-controlled trial. BJOG. 2014;122:4:500-508. https://doi.org/10.1111/1471-0528.13192
  21. Zaitseva MA, Repina MA. The influence of progestogen preparations on the risk of complications in late pregnancy. Vestnik Severo-Zapadnogo gosudarstvennogo medicinskogo universiteta im. I.I. Mechnikova. Sankt-Petersburg. 2016;8:2:54-59. (In Russ.)
  22. Arshakyan AK, Zarochentseva NV, Titchenko YuT, Men’shikova NS. Optimization of the management tactics for patients with recurrent miscarriage and chronic endometritis at the pregravid preparation stage: Rossiiskii vestnik akushera-ginekologa. 2017;17: 5:29-34. (In Russ.)
  23. Bogdanova AM, Glukhov EYu, Dikke GB. The use of low-frequency ultrasound in the complex treatment of the hypoplastic variant of chronic endometritis. Akusherstvo i ginekologiya. 2017;2:90-96. (In Russ.) https://doi.org/10.18565/aig.2017.2.90-6
  24. Glukhov EYu, Bogdanova AM, Kozyreva EN. Low-frequency ultrasound treatment for patients with chronic endometritis and different types of infertility. Rossiiskiy vestnik akushera-ginekologa. 2015;1:15:32-37. (In Russ.) https://doi.org/10.17116/rosakush201515132-37
  25. Papanikolaou EG, Kyrou D, Zervakakou G, Efstathia Paggou, Humaidan P. Follicular HCG endometrium priming for IVF patients experiencing resisting thin endometrium. A proof of concept study. Journal of Assisted Reproduction and Genetics. 2013;30:10:1341-1345. https://doi.org/10.1007/s10815-013-0076-0
  26. Motovilova TM, Kachalina TS, Zinov’eva OS, Bogatova ME, Chikalova KI, Kozlova NA. The role of endomethriopathy in the issue of reproductive failures and variants of its correction. Meditsinskii al’manakh. 2017;6:51:80-83. (In Russ.) https://doi.org/10.21145/2499-9954-2017-6-80-83
  27. Lysenko OV, Rozhdestvenskaya TA. The problem of «thin» endometrium in reproductive medicine: experience of application of recombinant Interleukin-2 to prepare patients to assisted reproductive technologies programs. Zhurnal akusherstva i zhenskikh boleznei. 2017;66:4:46-50. (In Russ.) https://doi.org/10.17816/JOWD66446-50
  28. Zadehmodarres S, Salehpour S, Saharkhiz N, Nazari L. Treatment of thin, endometrium with autologous platelet-rich plasma: a pilot study. JBRA Assist Reprod. 2017;21:1:54-56. https://doi.org/10.5935/1518-0557.20170013
  29. Kuznetsova IV, Zemlina NS, Rashidov TN, Kovalenko MA. The problem of thin endometrium and possible solutions. Effektivnaya farmakoterapiya. Akusherstvo i ginekologiya. 2015;1(5):42-49. (In Russ.)
  30. Kunicki M, Lukaszuk K, Woclawek-Potocka I, Liss J, Kulwikowska P, Szczyptanska J. Evaluation of granulocyte colony-stimulating factor effects on treatment-resistant thin endometrium in women undergoing in vitro fertilization. Biomed Res Int. 2014;1-5. https://doi.org/10.1155/2014/913235
  31. Li J, Mo S, Chen Y. The effect of G-CSF on infertile women undergoing IVF treatment: a metaanalysis. Systems Biology in Reproductive Medicine. 2017;63:4:239-247. https://doi.org/10.1080/19396368.2017.1287225
  32. Krasnopol’skaya KV, Fedorov AA, Ershova IYu, Aleksandrova VR. Clinical outcomes of eco programs with donor oocytes using endometrial scratching technology in patients with moderate and extreme lag in endometrial development. Meditsinskii alfavit. 2017; 1:3(300):46-50. (In Russ.)
  33. Orazov MR, Radzinskiy VE, Khamoshina MB, Kaygorodova LA, Toktar LR, Pokul’ LV, Tulupova MS. «Thin» endometrium — a modern view of the problem. Farmateka. 2018;6:359. (In Russ.)
  34. Chen Y, Liu L, Luo Y, Chen M, Huan Y, Fang R. Effects of aspirin and intrauterine balloon on endometrial repair and reproductive prognosis in patients with severe Intrauterine adhesion: a prospective cohort study. Biomed Res Int. 2017;1-8. https://doi.org/10.1155/2017/8526104
  35. Hsieh YY, Tsai HD, Chang CC. Low-dose aspirin for infertile women with thin endometrium receiving intrauterine insemination: a prospective, randomized study. J Assist Reprod Genet. 2000;17:174-177.
  36. Urman B, Mercan R, Alatas C, Balaban B, Isiklar A, Nuhoglu A. Low-dose aspirin does not increase implantation rates in patients undergoing intracytoplasmic sperm injection: a prospective randomized study. J Assist Reprod Genet. 2000;17:586-590.
  37. Sher G, Fisch JD. Effect of vaginal sildenafil on the outcome of in vitro fertilization (IVF) after multiple IVF failures attributed to poor endometrial development. Fertil Steril. 2002;78:1073-1076. https://doi.org/10.1016/s0015-0282(02)03375-7
  38. Takasaki A, Tamura H, Miwa I, Taketani T, Shimamura K, Sugino N. Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium. Fertil Steril. 2010;93:1851-1858. https://doi.org/10.1016/j.fertnstert.2008.12.062
  39. Mohamed Abdel Razik, Seham El-Berry, Ahmed El-Nezamy, Ahmed Saad & Ahmed Abdel Wahab. Nitric oxide donors increase the pregnancy rate in patients with unexplained infertility undergoing clomiphene citrate stimulation and intrauterine insemination: a randomized controlled pilot study. Gynecological Endocrinology. 2016;33:199-202. https://doi.org/10.1080/09513590.2016.1240775
  40. Rodger MA, Carrier M, Le Gal G, Martinelli I, Perna A, Rey E. Meta-analysis of low-molecular-weight heparin to prevent recurrent placenta-mediated pregnancy complications. Blood. 2013;123(6):822-828. https://doi.org/10.1182/blood-2013-01-478958
  41. Safdarian L, Najmi Z, Aleyasin A. Recurrent IVF failure and hereditary thrombophilia. Iran J Reprod Med. 2014;12(7):467-470.
  42. Melkozerova OA, Bashmakova NV, Chistyakova GN. Diagnostics program of endometral receivability disorders in patients with reproductive failures. Ural’skii meditsinskii zhurnal. 2017;9:119-127. (In Russ.)

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.