Role of pro- and antiangiogenic factors in the diagnosis of different forms of hypertensive states of pregnancy

Makarov O.V.; Volkova E.V.; Dzhokhadze L.S.

doi:https://doi.org/

Makarov O.V.

Kafedra akusherstva i ginekologii lechebnogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Volkova E.V.

Kafedra akusherstva i ginekologii lechebnogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Dzhokhadze L.S.

Kafedra akusherstva i ginekologii lechebnogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Role of pro- and antiangiogenic factors in the diagnosis of different forms of hypertensive states of pregnancy

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Makarov O.V., Volkova E.V., Dzhokhadze L.S.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2012;12(3): 15‑20

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Makarov OV, Volkova EV, Dzhokhadze LS. Role of pro- and antiangiogenic factors in the diagnosis of different forms of hypertensive states of pregnancy. Russian Bulletin of Obstetrician-Gynecologist. 2012;12(3):15‑20. (In Russ.)

Подписка 2026 Российский вестник акушера-гинеколога (Russian Bulletin of Obstetrician-Gynecologist)

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Abstract:

Arterial hypertension of pregnancy is one of the major causes of perinatal pathology, maternal diseases, and deaths worldwide. The accumulated data suggest that the balance between placental growth factor, vascular endothelial growth factor, and their receptors plays an important role in the processes of placental angiogenesis and development. In this paper the authors consider vascular growth factors in the context of the diagnosis of different forms of arterial hypertension of pregnancy. It may be suggested that antiangiogenic factors may be specific markers to predict and diagnose preeclampsia.

Keywords:

pregnancy; preeclampsia; different forms of arterial hypertension; angiogenesis; vascular endothelial growth factor; placental growth factor

antiangiogenic factors

Authors:

Makarov O.V.

Kafedra akusherstva i ginekologii lechebnogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Volkova E.V.

Kafedra akusherstva i ginekologii lechebnogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

Dzhokhadze L.S.

Kafedra akusherstva i ginekologii lechebnogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta

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