Aging of the human body leads to a gradual reduction in the reserve of adaptive capability, formation of a fragility state — increased vulnerability to impact of various factors. Investigation of the clinical manifestations of sarcopenia (SP) in elderly and senile men and women is relevant for the prediction, prevention and selection of methods of rehabilitation medicine.
OBJECTIVE
To study clinical manifestations of sarcopenia of different severity in elderly and senile men and women in the Tyumen region.
MATERIAL AND METHODS
A total of 752 persons were included in the study, among them 370 women and 91 men were 60—74 years old, 230 women and 61 men were aged 75 and older. All citizens were examined in accordance with the European consensus on sarcopenia protocol, including bioimpedansometry (InBody) and SarQoL questionnaire.
RESULTS
A preliminary assessment revealed a high incidence of probabilistic SP in the elderly age group, in men more often than in women. Men had a higher incidence of confirmed SP than women — 21.3 and 10% respectively (p=0.018). There were no statistically significant differences between women and men in the incidence of severe SP, as well as in the incidence of muscle weakness, rapid fatigue on exertion, decreased appetite detection depending on the severity of SP. Nevertheless, a number of gender differences has been identified in the groups with varying SP severity in terms of weight loss as well as strength and function of skeletal muscle decrease.
CONCLUSION
Gender-specific clinical parameters, prevalence and development risk factors of sarcopenia by sex and age should be further investigated that will help to develop the most effective preventive and corrective measures of rehabilitation medicine.