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Sergeeva V.A.

Kursk State Medical University;
Kursk Regional Children’s Hospital No. 2

Lipatova T.E.

Saratov State Medical University named after V.I. Razumovsky

Sarcopenia associated with COVID-19

Authors:

Sergeeva V.A., Lipatova T.E.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2022;25(11): 105‑112

DOI: 10.17116/profmed202225111105

Read: 4814 times

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Table of contents

SARCOPENIA ASSOCIATED WITH COVID-19
SARCOPENIA ASSOCIATED WITH COVID-19

To cite this article:

Sergeeva VA, Lipatova TE. Sarcopenia associated with COVID-19. Russian Journal of Preventive Medicine. 2022;25(11):105‑112. (In Russ.)
https://doi.org/10.17116/profmed202225111105

 
Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

COVID-19 convalescents are at risk of developing acute sarcopenia. In elderly patients, the risk is exceptionally high, given the presence of predisposing factors and the initial sarcopenic state before the onset of infection. This phenotype is referred to as «acute chronic» sarcopenia in the literature. It is now known that sarcopenia is associated with an increased risk of falls, fractures, and hospital admissions, reduced quality of life, disability, higher incidence of hospital-acquired infection in older patients, mortality, and according to recent data, the risk of developing adverse COVID-19 outcomes. Therefore, timely diagnostic and preventive measures can be crucial in increasing survival and improving the quality of life in patients with sarcopenia. The review analyzed data from publicly available scientific sources from PubMed/MedLine, Elsevier, and eLibrary, accumulated over the pandemic years. Also, a comprehensive evaluation of various factors during the new coronavirus infection potentiating the development and progression of sarcopenia was performed. Understanding and further enhancing knowledge of the pathogenetic mechanisms of muscle tissue damage associated with COVID-19 is necessary to develop different management strategies and effective preventive measures for such patients.

Keywords:

sarcopenia
COVID-19
SARS-CoV-2
muscle tissue
pathogenesis
aging

Authors:

Sergeeva V.A.

Kursk State Medical University;
Kursk Regional Children’s Hospital No. 2

Lipatova T.E.

Saratov State Medical University named after V.I. Razumovsky

Received:

16.06.2022

Accepted:

06.09.2022

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