Biome depletion hypothesis and ulcerative colitis — is there connection?

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Bikbavova G.R.

Omsk State Medical University

Livzan M.A.

Omsk State Medical University

ORCID: 0000-0002-6581-7017

Turchaninov D.V.

Omsk State Medical University

Tretyakova T.V.

Omsk Regional Clinical Hospital

Biome depletion hypothesis and ulcerative colitis — is there connection?

Authors:

Bikbavova G.R., Livzan M.A., Turchaninov D.V., Tretyakova T.V.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2020;23(6‑2): 52‑56

DOI: 10.17116/profmed20202306252

Read: 1123 times

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To cite this article:

Bikbavova GR, Livzan MA, Turchaninov DV, Tretyakova TV. Biome depletion hypothesis and ulcerative colitis — is there connection? Russian Journal of Preventive Medicine. 2020;23(6‑2):52‑56. (In Russ.)
https://doi.org/10.17116/profmed20202306252

Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)

Использование инфографики авторами научных работ

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Abstract:

PURPOSE OF THE STUDY

To assess the significance of surrogate markers of the biome depletion hypothesis in the development of ulcerative colitis.

MATERIAL AND METHODS

Active questioning (interviews) of 81 patients with ulcerative colitis and 39 healthy respondents was carried out. The main surrogate markers of the biome depletion hypothesis have been investigated. The information about the family history was analyzed.

RESULTS

The following factors are significant in the development of ulcerative colitis: insufficient intake of vegetables and fruits; increased consumption of sugar with tea and/or coffee; emotional and mental stress. More than ¹/₂ of the patients directly associated the onset of the disease with the stress they suffered. Patients with ulcerative colitis indicated that their close relatives (parents, siblings) were significantly more likely to suffer from autoimmune and oncological diseases of various localization compared with healthy responders.

CONCLUSION

The study confirms that modern diet and lifestyle habits contribute to the development of ulcerative colitis. Confirmation of the biome depletion hypothesis requires further investigations.

Keywords:

ulcerative colitis

biome depletion

intestinal microbiota

Authors:

Bikbavova G.R.

Omsk State Medical University

Livzan M.A.

Omsk State Medical University

ORCID: 0000-0002-6581-7017

Turchaninov D.V.

Omsk State Medical University

Tretyakova T.V.

Omsk Regional Clinical Hospital

Received:

20.03.2020

Accepted:

02.06.2020

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References:

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