Etiological and pathogenetic factors of ovarian dysfunction in women of reproductive age

Andreeva E.N.; Sheremetyeva E.V.; Adamyan L.V.

doi:https://doi.org/10.17116/repro20202606134

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Abstract:

In recent decades, the Russian government has set itself the task of solving the demographic situation in the country. Therefore, the clinician pays special attention to the reproductive period of a woman, violations in which can lead to infertility. Menstrual irregularities are a manifestation of various pathological conditions associated not only with disorders in the female reproductive system, but also with general systemic and endocrine diseases. Menstrual irregularities are characterized by a change in the cycle, duration and volume of menstrual blood loss. Since the 80s, the frequency of menstrual irregularities has increased by more than 7 times. A clinician who is primarily addressed by a woman of reproductive age with an menstrual irregularities must not only draw up a plan for examining a woman, but most importantly collect a detailed medical history, including physical status (for example, calculating body mass index), eating habits, sports history, taking medications (including dietary supplements, vitamins), to analyze the relationship of menstrual irregularities with epigenetic factors of a woman’s life. Thanks to a comprehensive examination, survey, examination of women of the reproductive period with menstrual irregularities, a rational approach within the framework of therapeutic tactics is possible.

Keywords:

menstrual cycle

functional hypothalamic amenorrhea

folate

vitamin D

stress

sports

bad habits

Authors:

Andreeva E.N.

Endocrinology Research Centre;
Moscow State University of Medicine and Dentistry

ORCID: 0000-0003-4979-7420

Sheremetyeva E.V.

A.I. Evdokimov Moscow State University of Medicine and Dentistry

ORCID: 0000-0001-7177-0254

Adamyan L.V.

Moscow State Medical and Dental University named after A.I. Evdokimov

SPIN RSCI: 9836-2713
Scopus AuthorID: 7006372422
ResearcherID: Q-1722-2018
ORCID: 0000-0002-3253-4512

Received:

14.05.2020

Accepted:

22.06.2020

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References:

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