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Savina V.A.

International center for reproductive medicine

Isakova E.V.

International center for reproductive medicine

Korsak V.S.

International center for reproductive medicine

The role of growth factors in the therapeutic effect of platelet-rich plasma on the endometrium (review)

Authors:

Savina V.A., Isakova E.V., Korsak V.S.

More about the authors

Journal: Russian Journal of Human Reproduction. 2020;26(5): 91‑98

DOI: 10.17116/repro20202605191

Read: 4435 times

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Table of contents

THE ROLE OF GROWTH FACTORS IN THE THERAPEUTIC EFFECT OF PLATELET-RICH PLASMA ON THE ENDOMETRIUM (REVIEW)
THE ROLE OF GROWTH FACTORS IN THE THERAPEUTIC EFFECT OF PLATELET-RICH PLASMA ON THE ENDOMETRIUM (REVIEW)

To cite this article:

Savina VA, Isakova EV, Korsak VS. The role of growth factors in the therapeutic effect of platelet-rich plasma on the endometrium (review). Russian Journal of Human Reproduction. 2020;26(5):91‑98. (In Russ.)
https://doi.org/10.17116/repro20202605191

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Platelet-rich plasma (PRP) is used in many fields of medicine. For several years, PRP has been used in assisted reproductive technologies with insufficient endometrial thickness, as well as in recurrent implantation failure. Moreover, the mechanism of action of PRP on the endometrium has not been fully studied. The purpose of the literature review is to present current data on the role of growth factors in the therapeutic effect of PRP on the endometrium. Analysis and synthesis of data available in the literature showed that the growth factors released during platelet activation with PRP are able to enhance the proliferation of endometrial cells, increase its vascularization, mediate the action of steroid hormones, and also positively affect the tolerance of the immune system locally. It seems reasonable that all of these effects are able to comprehensively affect the endometrium, increasing its thickness and improving its receptivity.

Keywords:

platelet-rich plasma (PRP)
reproductive techniques
assisted
endometrium

Authors:

Savina V.A.

International center for reproductive medicine

Isakova E.V.

International center for reproductive medicine

Korsak V.S.

International center for reproductive medicine

Received:

31.03.2020

Accepted:

22.05.2020

Close metadata

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