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Timokhina E.S.

Kafedra éndokrinologii i diabetologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

Saprina T.V.

GBOU VPO "Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava RF, Tomsk

Prokhorenko T.S.

Kafedra éndokrinologii i diabetologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

Vorozhtsova I.N.

GBOU VPO "Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii, Tomsk

THE FREQUENCY OF AUTOANTIBODIES TO ISLET CELLS DETECTION AND THE ROLE OF AUTOIMMUNITY IN THE DEVELOPMENT OF GESTATIONAL DIABETES

Authors:

Timokhina E.S., Saprina T.V., Prokhorenko T.S., Vorozhtsova I.N.

More about the authors

Journal: Russian Journal of Human Reproduction. 2012;(5): 107‑110

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THE FREQUENCY OF AUTOANTIBODIES TO ISLET CELLS DETECTION AND THE ROLE OF AUTOIMMUNITY IN THE DEVELOPMENT OF GESTATIONAL DIABETES
THE FREQUENCY OF AUTOANTIBODIES TO ISLET CELLS DETECTION AND THE ROLE OF AUTOIMMUNITY IN THE DEVELOPMENT OF GESTATIONAL DIABETES

To cite this article:

Timokhina ES, Saprina TV, Prokhorenko TS, Vorozhtsova IN. THE FREQUENCY OF AUTOANTIBODIES TO ISLET CELLS DETECTION AND THE ROLE OF AUTOIMMUNITY IN THE DEVELOPMENT OF GESTATIONAL DIABETES. Russian Journal of Human Reproduction. 2012;(5):107‑110. (In Russ.)

Подписка 2025-2 (Russian Journal of Human Reproduction)
 
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The purpose of the study was to determine the carrier frequency of autoantibodies to Β-cells in the pancreas and thyroid gland in pregnant women with and without impaired glucose metabolism, the role of autoantibodies in the development of carbohydrate metabolism disorders and their role in gestational and perinatal complications. The prevalence of autoantibodies to islet cells of the pancreas in pregnant women with GDM has significant ethnic features. One of the three studied autoantibodies was found in 13.2% of women with GDM and in 9.8% of women without disorders of carbohydrate metabolism.

Keywords:

gestational diabetes
autoantibodies
pregnancy

Authors:

Timokhina E.S.

Kafedra éndokrinologii i diabetologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

Saprina T.V.

GBOU VPO "Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava RF, Tomsk

Prokhorenko T.S.

Kafedra éndokrinologii i diabetologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

Vorozhtsova I.N.

GBOU VPO "Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii, Tomsk

List of references:

  1. Ametov A.S., Kazei N.S., Murashko L.E., Trusova N.V. Gestatsionnyi sakharnyi diabet. Mezhdunarodnaya programma "Diabet". Yaroslavl' 1995; 30.
  2. Kostenko I.V., Rogozhina I.E., Sukhankina G.V. Struktura razvitiya faktorov riska, rasprostranennost', diagnostika i metody lecheniya gestatsionnogo sakharnogo diabeta (obzor). Saratov nauchno-med zhurn 2011; 2: 542-546.
  3. Wilson L.G. Gestational diabetes: universal or selective screening? MJA 2001; 2: 113-114.
  4. Fuchtenbusch M., Ferber K., Standl E. Prediction of type 1 diabetes postpartum in patients with gestational diabetes mellitus by combined islet cell autoantibody screening: a prospective multicenter study. Diabetes Care 1997; 9: 59-67.
  5. Nilsson C., Ursing D., Törn C. Presence of GAD antibodies during gestational diabetes mellitus predicts type 1 diabetes. Diabetes Care 2007; 8: 22-26.
  6. Algoritmy spetsializirovannoi meditsinskoi pomoshchi bol'nym sakharnym diabetom, 5-e izd. Pod red. I.I. Dedova, M.V. Shestakovoi. M 2011; 115-117.

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