The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Podzolkova N.M.

Kafedra akusherstva i ginekologii Rossiĭskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia, Moskva

Koloda Iu.A.

Kafedra akusherstva i ginekologii Rossiĭskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia, Moskva

Podzolkov A.V.

Kafedra éndokrinologii Pervogo MGMU im. I.M. Sechenova

INFertility Therapy in obese patients: modern trends

Authors:

Podzolkova N.M., Koloda Iu.A., Podzolkov A.V.

More about the authors

Journal: Russian Journal of Human Reproduction. 2012;(3): 37‑41

Read: 4822 times

Download PDF (RU)
Contact the author
Table of contents

INFERTILITY THERAPY IN OBESE PATIENTS: MODERN TRENDS
INFERTILITY THERAPY IN OBESE PATIENTS: MODERN TRENDS

To cite this article:

Podzolkova NM, Koloda IuA, Podzolkov AV. INFertility Therapy in obese patients: modern trends. Russian Journal of Human Reproduction. 2012;(3):37‑41. (In Russ.)

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Modern view on the expe­rimental creation of endo­metriosis in animal models (own data). Russian Journal of Human Reproduction. 2024;(6):55-60
Expe­rimental mode­ling, prevention, and treatment of endo­metriosis-associated adhe­sion formation in NIH/3T3 fibroblast cell line using bovhyaluronidase azoximer (in vitro). Russian Journal of Human Reproduction. 2024;(6):61-72
The secretome of peri­pheral blood mono­nuclear cells in the therapy of patients with “thin” hypo­plastic endo­metrium and infe­rtility. Russian Journal of Human Reproduction. 2024;(6):81-98
Reproductive aspe­cts in the treatment of colo­rectal endo­metriosis. Russian Journal of Human Reproduction. 2024;(6):140-148
Modern view on the etiology of gallstone disease in children. Russian Journal of Evidence-Based Gastroenterology. 2024;(4):59-68
Meta­bolic syndrome and anti­psychotic therapy of schi­zophrenia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):165-170
Options for the surgical technique of lapa­roscopic sleeve gastrectomy for prevention and treatment of gastroesophageal reflux in patients with obesity. Endo­scopic Surgery. 2024;(6):57-68
Problems of regu­lar medi­cal check-up orga­nization of young males aged 15—17 years with cardiometabolic diseases. Russian Journal of Preventive Medi­cine. 2024;(12):81-87
Application of modern methods for acti­vation of brain functions in obese patients (literature review). Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;(6):54-61
Comparative analysis of the state of the microvasculature of the oral mucosa in persons with meta­bolic syndrome in the aspect of orthopedic dental reha­bilitation. Stomatology. 2024;(6-2):15-22
Abstract:

The problem of infertility treatment in patients with obesity is discussed. Results of original studies, metaanalysis and systematic reviews are presented.

Keywords:

infertility
obesity
metabolic syndrome
metformi

Authors:

Podzolkova N.M.

Kafedra akusherstva i ginekologii Rossiĭskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia, Moskva

Koloda Iu.A.

Kafedra akusherstva i ginekologii Rossiĭskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia, Moskva

Podzolkov A.V.

Kafedra éndokrinologii Pervogo MGMU im. I.M. Sechenova

Close metadata

References:

  1. Sukhikh G.T., Nazarenko T.A. (red). Besplodnyi brak. Sovremennye podkhody k diagnostike i lecheniyu. M: GEOTAR-Media 2010; 784.
  2. Blagosklonnaya L.V., Krasil'nikova E.I., Babenko A.Yu. Ozhirenie i ego potentsial'naya rol' v razvitii metabolicheskogo sindroma. Novye Sankt-Peterburgskie vrachebnye vedomosti 1998; 4: 6: 43-48.
  3. Gevorkyan M.A., Manukhin I.B., Tumilovich L.G. Klinicheskie lektsii po ginekologicheskoi endokrinologii. M: GEOTAR-Media 2006; 234.
  4. Roitenberg G.E. (red.). Metabolicheskii sindrom. M: Med-press-inform 2007; 224.
  5. Dedov I.I., Mel'nichenko G.A.(red.) Ozhirenie: etiologiya, patogenez, klinicheskie aspekty. M: MIA 2004; 449.
  6. Podzolkova N.M., Anshina M.B., Shamugiya N.L., Ablyaeva E.Sh., Koloda Yu.A. Vliyanie massy tela na effektivnost' programm vspomogatel'nykh reproduktivnykh tekhnologii. Mezhdunarodnyi kongress po reproduktivnoi meditsine "Reproduktivnoe zdorov'e i planirovanie sem'i", 2-i: Materialy. M 2008; 366.
  7. Dedov I.I., Andreeva E.N., Pishchulin A.A., Karpova E.A. Sindrom giperandrogenii u zhenshchin. M 2006; 40.
  8. Dedov I.I., Mel'nichenko G.A. (red.). Sindrom polikistoznykh yaichnikov. M: MIA 2007; 242-272.
  9. Krasnopol'skii V.I., Logutova L.S., Serova O.F., Tuanova V.A., Zarochentseva N.V., Pozdnyakova T.I. Sindrom polikistoznykh yaichnikov. M: Adamant''; 40.
  10. Abu Hashim H., El Lakany N., Sherief L. Combined metformin and clomiphene citrate versus laparoscopic ovarian diathermy for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized controlled trial. J Obstet Gynaecol Res 2011; 37: 3: 169-177.
  11. Al-Azemi M., Omu F.E., Omu A.E. The effect of obesity on the outcome of infertility management in women with polycystic ovary syndrome. Arch Gynecol Obstet 2004; 270: 205-210.
  12. Batukan C., Baysal B. Metformin improves ovulation and pregnancy rates in patients with polycystic ovary syndrome. Arch Gynecol Obstet 2001; 265: 124-127.
  13. Cheng J., Lv J., Li C.Y., Xue Y., Huang Z., Zheng W. Clinical outcomes of ovulation induction with metformin, clomiphene citrate and human menopausal gonadotrophin in polycystic ovary syndrome. J Int Med Res 2010; 38: 4: 1250-1258.
  14. Costello M.F., Chapman M., Conway U. A systematic review and meta-analysis of randomized controlled trials on metformin co-administration during gonadotrophin ovulation induction or IVF in women with polycystic ovary syndrome. Hum Reprod 2006; 21: 6: 1387-1399.
  15. De Leo V., Musacchio M.C., Piomboni P., Di Sabatino A., Morgante G. The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications. Eur J Obstet Gynecol Reprod Biol 2011; 157: 1: 63-66.
  16. Ehrmann D.A., Cavaghan M.K., Imperial J. et al. Effects of metformin on insulin secretion, insulin action and ovarian steroidogenesis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 1997; 82: 524-530.
  17. Farquhar C., Gillett W. Prioritising for fertility treatments-should a high BMI exclude treatment? BJOG 2006; 113: 1107-1109.
  18. Fedorcsak P., Dale P.O., Storeng R., Abyholm T., Tanbo T. The effect of metformin on ovarian stimulation and in vitro fertilization in insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross-over trial. Gynecol Endocrinol 2003; 17: 3: 207-214.
  19. Fedorcsák P., Storeng R., Dale PO, Tanbo T., Torjesen P., Urbancsek J., Abyholm T. Leptin and leptin binding activity in the preovulatory follicle of polycystic ovary syndrome patients. Scand J Clin Lab Inv 2000; 60: 8: 649-655.
  20. Fulghesu A.M., Villa P., Pavone V. et al. The impact of insulin secretion on the ovarian response to exogenous gonadotropins in polycystic ovary syndrome. J Clin Endocrinol Metab 1997; 82: 644-648.
  21. Gilbert C., Valois M., Koren G. Pregnancy outcome after first-trimester exposure to metformin: a metaanalysis. Fertil Steril 2006; 86: 3: 658-663.
  22. Hollmann M. Impact of waist-hip-ratio and body-mass-index on hormonal and metabolic parameters in young, obese women. Int J Obes Relat Metab Dis 1997; 21: 6: 476-483.
  23. Hugues J.N. Impact of overweight on the outcome of ovarian stimulation. Bull Acad Natl Med 2008; 192: 4: 661-670.
  24. Kjotrod S.B., von During V. Carlsen. Metformin treatment before IVF/ICSI in women with polycystic ovary syndrome: a prospective, randomized, double blind study. Human Reprod 2004; 19: 1315-1322.
  25. Legro R.S., Barnhart H.X., Schlaff W.D. Clomiphen, metformin, or both, for infertility in the polycystic ovary syndrome. NEJM 2007; 356: 551-566.
  26. Li M., Song J., Chen S.L. Association of the clinical characteristics and the IVF-ET outcome in infertile women with polycystic ovarian syndrome of different subtypes. Nan Fang Yi Ke Da Xue Xue Bao 2009; 29: 2: 224-227.
  27. Li X.J., Yu Y.X., Liu C.Q., Zhang W., Zhang H.J., Yan B., Wang L.Y., Yang S.Y., Zhang S.H. Metformin vs thiazolidinediones for treatment of clinical, hormonal and metabolic characteristics of polycystic ovary syndrome: a meta-analysis. Clin Endocrinol (Oxford) 2011; 74: 3: 332-339.
  28. McCormick B., Thomas M., Maxwell R. Effects of polycystic ovarian syndrome on in vitro fertilization-embryo transfer outcomes are influenced by body mass index. Fertil Steril 2008; 90: 6: 2304-2309.
  29. Moll E., Bosuyt P.M., Korevaar J.C., Lambalk C.B., van der Veen F. Effect of clomiphen citrate plus metormin and clomiphen citrate plus placebo on induction ovulation in women with newly diagnosed polycystic ovary syndrome: Randomized double-blind clinical trial. BMJ 2006; 332: 1485.
  30. Moll E., van der Veen F., van Wely M. The role of metformin in polycystic ovary syndrome: a systematic review. Hum Reprod Update 2007;13: 6: 527-537.
  31. Nieuwenhuis-Ruifrok A.E., Kuchenbecker W.K., Hoek A., Middleton P., Norman R.J. Insulin sensitizing drugs for weight loss in women of reproductive age who are overweight or obese: systematic review and meta-analysis. Hum Reprod Update 2009; 15: 1: 57-68.
  32. Norman R.J., Noakes M., Wu R., Davies M.J., Moran L., Wang J.X. Improving reproductive performance in overweight/obese women with effective weight management. Hum Reprod Update 2004; 10: 267-280.
  33. Onalan G., Pabuccu R., Goktolga U., Ceyhan T., Bagis T., Cincik M. Metformin treatment in patients with polycystic ovary syndrome undergoing in-vitro fertilization: a prospective, randomized trial. Fertil Steril 2005; 84: 798-801.
  34. Palomba S., Orio F., Nardo L.G., Falbo A., Russo T., Corea D. Metformin administration versus laparoscopic ovarian diathermy in clomiphen citrate-resistant women with polycystic ovary syndrome: a prospective, randomized double-blind placebo-controlled trial. J Clin Endocrinol Metab 2004; 89: 4801-4809.
  35. Pasquali R., Antenucci D., Casimirri F., Venturoli S., Paradisi R., Fabbri R. et al. Clinical and hormonal characteristics of obese and amenorrheic women before and after weight loss. J Clin Endocrinol Metab 1989; 68: 173-179.
  36. Tang T., Granville J., Orsi N., Barth J.H., Balen A.H. The use of metformin for women with PCOS undergoing IVF treatment. Human Reprod 2006; 21: 1416-1425.
  37. Tang T., Lord J.M., Norman R.J., Yasmin E., Balen A.H. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. Cochrane Database Syst Rev 2010; 20: 1: CD003053.
  38. Tso L.O., Costello M.F., Albuquerque L.E., Andriolo R.B., Freitas V. Metformin treatment before and during IVF or ICSI in women with polycystic ovary syndrome. Cochrane Database Syst Rev 2009; 2: CD006105.
  39. Wass P., Waldenstrom U., Rossner S. et al. An android body fat distribution in females impairs the pregnancy rate of in-vitro fertilization-embryo transfer. Hum Reprod 1997; 12: 2057-2060.
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.