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Unguryan V.M.

Kostroma Oncology Dispensary

Kazantsev A.N.

Kostroma Regional Oncology Dispensary;
B.V. Petrovsky Russian Scientific Center of Surgery;
Kostroma Regional Clinical Hospital named after E.I. Korolev

Abduragimov A.M.

I.I. Mechnikov North-Western State Medical University

Belov Yu.V.

B.V. Petrovsky Russian Scientific Center of Surgery;
I.M. Sechenov First Moscow State Medical University

Modern treatment methods for patients with liver metastases from uveal melanoma

Authors:

Unguryan V.M., Kazantsev A.N., Abduragimov A.M., Belov Yu.V.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2024;13(2): 74‑84

DOI: 10.17116/onkolog20241302174

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Table of contents

To cite this article:

Unguryan VM, Kazantsev AN, Abduragimov AM, Belov YuV. Modern treatment methods for patients with liver metastases from uveal melanoma. P.A. Herzen Journal of Oncology. 2024;13(2):74‑84. (In Russ.)
https://doi.org/10.17116/onkolog20241302174

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Uveal melanoma is a rare malignant neoplasm originating from the uveal tract of the eye. The liver is the most common site of metastasis, occurring in 70—90% of cases and becoming the sole site of metastasis in approximately 50% of observations. This literature review presents modern methods for treating liver metastases from uveal melanoma: immunotherapy, targeted therapy, oncolytic adenovirus therapy, chemoembolization, transarterial chemoembolization, drug-eluting bead therapy, immunoembolization, radioembolization, thermal ablation, isolated hepatic perfusion. The conclusion is drawn about the highest efficacy, safety, and availability of isolated hepatic perfusion compared to other treatment methods.

Keywords:

immunotherapy
targeted therapy
oncolytic adenovirus therapy
chemoembolization
transarterial chemoembolization
drug-eluting bead therapy
immunoembolization
radioembolization
thermal ablation
isolated hepatic perfusion

Authors:

Unguryan V.M.

Kostroma Oncology Dispensary

Kazantsev A.N.

Kostroma Regional Oncology Dispensary;
B.V. Petrovsky Russian Scientific Center of Surgery;
Kostroma Regional Clinical Hospital named after E.I. Korolev

Abduragimov A.M.

I.I. Mechnikov North-Western State Medical University

Belov Yu.V.

B.V. Petrovsky Russian Scientific Center of Surgery;
I.M. Sechenov First Moscow State Medical University

Received:

18.05.2023

Accepted:

26.07.2023

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