Risk of death from lung cancer among the liquidators of the consequences of the Chernobyl accident, employees of the enterprises of the nuclear industry

Tukov A.R.; Shafranskii I.L.; Biryukov A.P.; Prokhorova O.N.; Orlov Yu.V.

doi:https://doi.org/10.17116/onkolog20221105125

Tukov A.R.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Shafranskii I.L.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Biryukov A.P.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Prokhorova O.N.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Orlov Yu.V.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Risk of death from lung cancer among the liquidators of the consequences of the Chernobyl accident, employees of the enterprises of the nuclear industry

Authors:

Tukov A.R., Shafranskii I.L., Biryukov A.P., Prokhorova O.N., Orlov Yu.V.

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Journal: P.A. Herzen Journal of Oncology. 2022;11(5): 25‑30

DOI: 10.17116/onkolog20221105125

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Tukov AR, Shafranskii IL, Biryukov AP, Prokhorova ON, Orlov YuV. Risk of death from lung cancer among the liquidators of the consequences of the Chernobyl accident, employees of the enterprises of the nuclear industry. P.A. Herzen Journal of Oncology. 2022;11(5):25‑30. (In Russ.)
https://doi.org/10.17116/onkolog20221105125

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)

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OBJECTIVE

To assess the excess relative risk in terms of 1Sv on the basis of materials on the mortality of malignant neoplasms of workers in the nuclear industry — liquidators of the Chernobyl accident, as well as part of workers who worked or continue to work with sources of ionizing radiation.

MATERIALS AND METHODS

The data base of the Industry Register of persons exposed to radiation as a result of the Chernobyl accident was used in the work. Methods of cohort analysis of the accumulated mortality were used, based on Poisson regression. Estimates of the ERR at 1Sv were calculated using both Chernobyl doses and doses, accepted during professional work. The cohort comprises 12 663 males entered the Chernobyl exclusion zone from 1986 over 1990, summed person-years of observation — 253 288, for the follow-up period 183 deaths from lung cancer (ICD-10: C34-C34.9) were registered.

RESULTS

It is shown that in some cases, the risk estimates obtained by using doses, accepted during professional work are more realistic, in other cases both estimates have similar values. The radiation risk of lung cancer mortality were 0.45 [–0.02, 1.01] in the case of using the total doses.

CONCLUSION

An analysis of the radiation risk of death from lung cancer in the cohort of liquidators showed that for doses received only in the Chernobyl zone, the assessment of the excess relative risk indicates its absence. A reliable dose-effect is characterized by the risks obtained when using the total dose of the Chernobyl nuclear power plant and occupational exposure. An important problem of correctly calculating the risk of radiation-related diseases is the creation of a medical dosometric register of nuclear industry workers with doses received by a person from all types of exposure (professional, emergency, medical, natural).

Keywords:

radiation

excess relative risk

mortality

lung cancer

Chernobyl accident

Rosatom

branch Registr

Authors:

Tukov A.R.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Shafranskii I.L.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Biryukov A.P.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Prokhorova O.N.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Orlov Yu.V.

A.I. Burnazyan Federal Medical Biophysical Center — State Research Center of the Russian Federation

Received:

04.04.2022

Accepted:

31.05.2022

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