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Bychkova N.M.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of the Russian Federation, Moscow, Russia

Khmelevsky E.V.

P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, Moscow, Russian Federation

Current approaches to radiotherapy for skeletal metastastic lesions

Authors:

Bychkova N.M., Khmelevsky E.V.

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Journal: P.A. Herzen Journal of Oncology. 2019;8(4): 295‑302

DOI: 10.17116/onkolog20198041295

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To cite this article:

Bychkova NM, Khmelevsky EV. Current approaches to radiotherapy for skeletal metastastic lesions. P.A. Herzen Journal of Oncology. 2019;8(4):295‑302. (In Russ.)
https://doi.org/10.17116/onkolog20198041295

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According to autopsy data, the incidence of skeletal metastases is 40—45%. In cancer patients, most cases of pain syndrome are associated with the development of bone metastases. Skeletal metastases complicated by pathological fractures or spinal cord or peripheral nerve compression significantly lower quality of life in patients and still remain an actual problem for oncologists of various specialties. Radiotherapy along with surgical treatment and systemic drug therapy occupies an important place in the treatment of skeletal metastatic lesions. Various local exposure techniques (3D conformal radiation therapy and stereotactic body radiotherapy (SBRT)), as well as systemic radiotherapy with radiopharmaceuticals based on 153Sm, 89Sr, 186Re, 188Re, 177Lu, 90Y, 131I, etc. are applied. The development of radiotherapy technologies expands indications first of all in case of oligometastatic lesions.

Keywords:

bone metastases
radiotherapy

Authors:

Bychkova N.M.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of the Russian Federation, Moscow, Russia

Khmelevsky E.V.

P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, Moscow, Russian Federation

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