Nontraditional radiotherapy regimens for non-small-cell lung cancer

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Radiotherapy (RT) plays an important role in the treatment of non-small-cell lung cancer (NSCLC) due to the fact that a considerable number of patients have contraindications to surgical treatment. However, the results of medical treatment for NSCLC cannot be considered satisfactory. Current techniques for treating RT can targetedly affect a tumor and minimize its negative impact on adjacent healthy tissues. This in turn opens the way for dose escalation and radiotherapeutic exposure optimization in each patient. This assumes particular importance in patients having contraindications to chemotherapy that needs the exposure to independent radical RT to be increased. The trials of the efficiency of different fractionation regimens have shown that the use of accelerated regimens is the most promising area in the treatment of NSCLC.

Keywords:

lung cancer

radiotherapy

nontraditional fractionation

Authors:

Ragulin Iu.A.

Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossii, Obninsk

Gogolin D.V.

A.F. Tsyb Medical Radiology Research Centre, Branch, National Medical Radiology Center, Ministry of Health of the Russian Federation, Obninsk, Russia

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