Lichen nitidus of Pinkus (LN) is a rare dermatosis that is more common in childhood. Its clinical presentation is characterized by isolated small multiple papules of flesh or light pink color, with a shiny surface, barely rising, sometimes accompanied by an itch. Localization of efflorescence — genitals, trunk, upper and lower extremities. The mucous membrane of the oral cavity is rarely affected. With skin irritation, the Koebner phenomenon may be observed. Clinical course of the condition may be different: some patients have spontaneous recovery in a short time, but often the process lasts for years, and is difficult to treat. In some cases, generalized form occurs. The treatment of LN depends on the severity of the clinical manifestations and the course of the disease. In mild forms of dermatosis, treatment is limited to the prescription of vitamins C, group B, antihistamines, and external anti-inflammatory drugs. In severe and generalized forms, corticosteroid drugs (topically or parenterally), aromatic retinoids are used. The prognosis of the disease is favorable: In 2/3 of the patients, the pathological process spontaneously resolves after about a year. In rare cases, rashes persist indefinitely. A clinical observation of a patient with generalized lichen nitidus is presented, in which, with the complex treatment, a pronounced therapeutic effect was achieved in 11 days. The treatment complex included intravenous transfusions of sodium chloride (250 ml drip No. 10), 10% calcium gluconate solution (6 ml intramuscularly No. 12), chloropyramine (1 ml intramuscularly No. 11 and 2/3 tablets orally, 2 times a day), external use Betamethasone ointment, 2% naphthalan paste, narrow-band phototherapy with a wavelength of 311 nm (nine procedures). This case is of clinical interest to dermatovenerologists because of the rare occurrence of the common form of the lichen nitidus of Pinkus.