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Koriukina E.B.

Regional Dermatoveneroloical Dispensary, Ekaterinburg

Khismatullina Z.R.

Bashkir State Medical University, Ministry of Health of the Russian Federation, Ufa, Russia, 450000

Golovyrina I.L.

MAUZ «Central City Hospital №3», Ekaterinburg, Russia

The role of emollients in the treatment of atopic dermatitis (in Russian only)

Authors:

Koriukina E.B., Khismatullina Z.R., Golovyrina I.L.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2019;18(1): 43‑48

DOI: 10.17116/klinderma20191801143

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THE ROLE OF EMOLLIENTS IN THE TREATMENT OF ATOPIC DERMATITIS (IN RUSSIAN ONLY)
THE ROLE OF EMOLLIENTS IN THE TREATMENT OF ATOPIC DERMATITIS (IN RUSSIAN ONLY)

To cite this article:

Koriukina EB, Khismatullina ZR, Golovyrina IL. The role of emollients in the treatment of atopic dermatitis (in Russian only). Russian Journal of Clinical Dermatology and Venereology. 2019;18(1):43‑48. (In Russ.)
https://doi.org/10.17116/klinderma20191801143

 
Подписка 2025-2 (Russian Journal of Clinical Dermatology and Venereology)
 
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Atopic dermatitis (AtD) is a chronic, multifactorial, immune-mediated pruritic dermatosis that significantly reduces the quality of patients' lives. Topical corticosteroids are the first-line drugs for the treatment of exacerbations of the disease. Emollients that improve the barrier function of the skin, reduce dryness and inflammation, are recommended for daily skin care at any stage of AtD. Objective: to conduct a comparative assessment of the action of lipid-restoring balm and agents containing 5% of panthenol, in combination therapy in patients of different ages, suffering from AtD. A total of 63 patients with mild and moderate forms of AtD were included in the open comparative study of the use of the drug lipid-restoring balm. The article presents an assessment of the dynamics of treatment of AtD using the SCORAD scale, Dermatology Specific Quality of Life (DSQL). Compared with the control group, there are pronounced differences in the value of the SCORAD index, which characterize the higher efficacy of the lipid-restoring balm in the treatment/management of AtD remission. On the 84th day of the study, the DSQL index in the group of individuals who used lipid-restoring balm was 2.4 points vs. 5.9 points in the group of participants who used the comparison product. The article presents clinical demonstrations of the results of the use of the lipid-restoring balm.

Keywords:

dry skin
atopic dermatitis
SCORAD
DSQL
skin barrier
emollients
lipid-restoring balm

Authors:

Koriukina E.B.

Regional Dermatoveneroloical Dispensary, Ekaterinburg

Khismatullina Z.R.

Bashkir State Medical University, Ministry of Health of the Russian Federation, Ufa, Russia, 450000

Golovyrina I.L.

MAUZ «Central City Hospital №3», Ekaterinburg, Russia

List of references:

  1. Minchenko AV, Zhukova OV, Lvov AN. Atopic dermatitis: new horizons of external therapy. Moscow Scientific and Practical Center for Dermatovenerology and Cosmetology of the DZM. 2017;S4:50-53. (In Russ.)
  2. Simpson EL, Bieber T, Eckert L, Wu R, Ardeleanu M, Graham NM, et al. Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults. J Am Acad Dermatol. 2016;74(3):491-498.
  3. Cambazard F, Lanz S, Natalizio A, Sirvent A. Evaluation of the efficacy of Topicrem AD-Baume Emollient versus a comparator on atopic dermatitis flare-ups in children. Therapeutiques en dermato-venerologie. 2016.
  4. World Allergy Organization, White book on allergy: update 2013, 2013. [Online]. Accessed 24 July 2017. www.worldallergy.org/UserFiles/file/WhiteBook2-2013-v8.pdf
  5. Federal clinical guidelines. Dermatovenereology 2015: Diseases of the skin. Sexually transmitted infections. 5th ed., Revised. and add. M. 2016. (In Russ.)
  6. Polikarpov AV, et al. Statistical Yearbook 2017, part 2: Incidence of the entire population of Russia in 2017. Moscow. 2018;142. Website of the Ministry of Health of the Russian Federation. (In Russ.) https://www.rosminzdrav.ru/ministry/61/22/stranitsa-979/statisticheskie-i-informatsionnye-materialy/statisticheskiy-sbornik-2017-god
  7. Kravchenya SS, Igonina IA, Bakulev AL. Combined external therapy of atopic dermatitis. Russian Journal of Clinical Dermatology and Venereology = Klinichaskaya dermatologiya i venerologiya. 2011;(1):41-44. (In Russ.)
  8. Federal clinical guidelines for the diagnosis and treatment of atopic dermatitis. Russian Association of Allergists and Clinical Immunologists. Moscow. 2013 12.23;28. (In Russ.)
  9. Federal clinical guidelines for the provision of medical care for children with atopic dermatitis. Ministry of Health of the Russian Federation, Union of Pediatricians of Russia, Russian Society of Dermatovenerologists and Cosmetologists, Russian Association of Allergologists and Clinical Immunologists. Eds. Baranova AA, Namazova-Baranova LS. M. 2015;32. (In Russ.)
  10. Araviyskaya E.R., Sokolovsky E.V. Skin barrier properties and basic care: innovation in theory and practice. Vestn dermatol venerol. 2010;(6):135-139 (In Russ.)
  11. Schegelskaya TYu. Modern means of skin care for children as the basis of basic therapy for atopic dermatitis. Saratov Med J. 2016;12(3):487-489. (In Russ.)
  12. Ring J, Alomar A, Bieber T, et al. Guidelines for treatment of atopic eczema (atopic dermatitis). Part I. J Eur Acad Dermatol Venereol. 2012;26(8):1045-1060.
  13. Kamaev AV, Trusova OV, Lyashenko NL, Makarova IV. Emolents in the treatment of atopic dermatitis in children: analysis of clinical and pharmacoeconomic efficacy. Rus J Allergy 2017;(4-5):98-107. (In Russ.)
  14. Belousova TA, Kail-Goryachkina MV. Personalized approach to the choice of basic therapy for dry skin. Con med. 2017;(2):38-42. (In Russ.)
  15. Khismatullina ZR, Zainullina ON. A modern approach to the external treatment of mild atopic dermatitis. Bashkortostan Med J. 2016;(5):168-171. (In Russ.)

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