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Zikiryakhodzhaev A.D.

Herzen Moscow Oncology Research Institute;
People’s Friendship University of Russia;
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Starkova M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Timoshkin V.O.

Herzen Moscow Oncology Research Institute

Indocyanine green in diagnostics and reconstructive surgery for breast cancer

Authors:

Zikiryakhodzhaev A.D., Starkova M.V., Timoshkin V.O.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2023;(9‑2): 20‑24

DOI: 10.17116/hirurgia202309220

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Table of contents

INDOCYANINE GREEN IN DIAGNOSTICS AND RECONSTRUCTIVE SURGERY FOR BREAST CANCER
INDOCYANINE GREEN IN DIAGNOSTICS AND RECONSTRUCTIVE SURGERY FOR BREAST CANCER

To cite this article:

Zikiryakhodzhaev AD, Starkova MV, Timoshkin VO. Indocyanine green in diagnostics and reconstructive surgery for breast cancer. Pirogov Russian Journal of Surgery. 2023;(9‑2):20‑24. (In Russ.)
https://doi.org/10.17116/hirurgia202309220

Подписка 2025-2 (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
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OBJECTIVE

To analyze the efficacy of sentinel lymph node detection using indocyanine green (ICG) in breast cancer.

MATERIAL AND METHODS

The study included 153 breast cancer patients (stage 0-I-II-III, cN0 or cN1-ycN0) between October 2022 and April 2023. All patients underwent sentinel lymph node biopsy using ICG.

RESULTS

Sentinel lymph node was successfully detected in 150 cases out of 153 ICG injections. Optimal period between ICG injection and its accumulation in regional lymph nodes was 10—12 min. Sensitivity of sentinel lymph node detection was 98.0% that exceeds the approximate value of radioisotope method adopted as a standard (96.9—97.2%), as well as sensitivity of proprietary blue dye (90.6—95.0%). Specificity of this method was 100%.

CONCLUSION

The authors’ experience regarding application of indocyanine green is consistent with numerous world statistics and proves the possibility of its effective use for sentinel lymph node biopsy. It is necessary to introduce this diagnostic method as a leading or alternative method for analysis of sentinel lymph node in national clinical guidelines.

Keywords:

indocyanine green
ICG
breast cancer
reconstructive surgery

Authors:

Zikiryakhodzhaev A.D.

Herzen Moscow Oncology Research Institute;
People’s Friendship University of Russia;
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Starkova M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Timoshkin V.O.

Herzen Moscow Oncology Research Institute

Received:

05.06.2023

Accepted:

12.07.2023

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