Magnetic resonance imaging in liver function analysis. Modern objective reality

Arutyunyants D.E.; Khovrin V.V.; Galyan T.N.; Kulichkin A.S.; Tarba N.S.; Filin A.V.; Metelin A.V.

doi:https://doi.org/10.17116/hirurgia202106289

Arutyunyants D.E.

Petrovsky Russian Scientific Center of Surgery

Khovrin V.V.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-6720-4126

Galyan T.N.

Petrovsky Russian Scientific Center of Surgery

Kulichkin A.S.

Petrovsky Russian Scientific Center of Surgery

Tarba N.S.

Petrovsky Russian Scientific Center of Surgery

Filin A.V.

Petrovsky National Research Centre of Surgery

Metelin A.V.

Petrovsky National Research Centre of Surgery

Magnetic resonance imaging in liver function analysis. Modern objective reality

Authors:

Arutyunyants D.E., Khovrin V.V., Galyan T.N., Kulichkin A.S., Tarba N.S., Filin A.V., Metelin A.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2021;(6‑2): 89‑94

DOI: 10.17116/hirurgia202106289

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To cite this article:

Arutyunyants DE, Khovrin VV, Galyan TN, Kulichkin AS, Tarba NS, Filin AV, Metelin AV. Magnetic resonance imaging in liver function analysis. Modern objective reality. Pirogov Russian Journal of Surgery. 2021;(6‑2):89‑94. (In Russ.)
https://doi.org/10.17116/hirurgia202106289

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

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Abstract:

Chronic liver disease is a serious worldwide problem because its progression is accompanied by liver fibrosis and cirrhosis at the terminal stages. Primary diagnosis and dynamic assessment of liver fibrosis are essential to determine the prognosis of disease and optimal treatment strategy. Long-term world experience in the use of gadoxetic acid (primovist, eovist) for diagnosis of liver diseases confirms its hepatotropic properties. Thus, magnetic resonance imaging (MRI) in hepatobiliary phase of contrast enhancement is valuable for differential diagnosis of focal liver lesions and assessment of liver structure and fibrotic changes. This review is devoted to the most common methods of contrast-enhanced MRI for assessment of liver function and correlation between severity of diffuse structural liver changes and gadoxetic acid accumulation in liver parenchyma. There is no a single method for MRI-based analysis of liver function that is confirmed by active researches in this direction. It was found that liver biopsy can by unnecessary in some cases if contrast-enhanced MRI with gadoxetic acid is available. The advantage of gadoxetic acid is also elimination properties. Indeed, biliary excretion ensures T1-weighted MR-cholangiography for additional assessment of patency, function and anatomy of the bile ducts. However, there are still several questions in this area that necessitates further research.

Keywords:

gadoxetic acid

MRI

liver function

diffuse liver diseases

liver fibrosis

cirrhosis

Authors:

Arutyunyants D.E.

Petrovsky Russian Scientific Center of Surgery

Khovrin V.V.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-6720-4126

Galyan T.N.

Petrovsky Russian Scientific Center of Surgery

Kulichkin A.S.

Petrovsky Russian Scientific Center of Surgery

Tarba N.S.

Petrovsky Russian Scientific Center of Surgery

Filin A.V.

Petrovsky National Research Centre of Surgery

Metelin A.V.

Petrovsky National Research Centre of Surgery

Received:

03.03.2021

Accepted:

11.04.2021

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References:

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