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Objective. To compare the results of open and laparoscopic interventions for PGDU complicated by advanced peritonitis. Material and methods. A retrospective analysis enrolled 172 patients with PGDU who underwent surgery for the period 2014—2016. The research was performed at the bases of the Department of Faculty-Based Surgery No. 1 of the Medical Faculty of the Pirogov Russian National Research Medical University. Further analysis enrolled 138 patients in accordance with inclusion and exclusion criteria (laparoscopic intervention — 116 patients, open surgery — 22). Propensity score matching (pseudorandomization) was applied after comparative analysis of patients’ characteristics and treatment outcomes in order to ensure maximum comparability of both groups. Results. Length of hospital-stay (7.1 vs. 9.8 days), incidence of extra-abdominal complications (6.3%. vs. 41.2%) and adverse events Clavien—Dindo grade II (6.3% vs. 35.3%) were significantly lower after minimally invasive surgery (p<0.05). Conclusion. Analysis of comparable groups of patients with PGDU complicated by peritonitis revealed that laparoscopic surgery is accompanied by significantly lower incidence of extra-abdominal postoperative complications and shorter hospital-stay compared with open surgery. Mortality and incidence of intra-abdominal postoperative complications were similar in both groups.

Authors:

Sazhin A.V.

Pirogov Russian National Research Medical University

SPIN RSCI: 7064-6369
Scopus AuthorID: 6701753208
ORCID: 0000-0001-6188-6093

Ivakhov G.B.

Pirogov Russian National Research Medical University & ,V.S. Savel’ev University Faculty Clinic, Moscow, Russia

Stradymov E.A.

Pirogov Russian National Research Medical University & ,V.S. Savel’ev University Faculty Clinic, Moscow, Russia

SPIN RSCI: 1739-3002
ORCID: 0000-0001-9414-7588

Petukhov V.A.

Department of faculty surgery named after S.I. Spasokukotskyi, School of general medicine, Pirogov Russian National Research Medical University, Moscow, Russia

Titkova S.M.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

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