Efficiency of combined application in complex treatment of widespread purulent peritonitis of the metabolic preparation, containing amber acid, inosine, riboflavin and nicotineamide, Citoflavin, a preparation of recombinant interleukin-2 with intracutaneous way of introduction and a preparation for a parenteral nutrition on a basis an omega-3-fat of acids is studied. It is established that the usage of the given scheme promotes authentic decrease in the maintenance in blood acute phase proteins (CRP, CRP-ultra), inhibitors of tissue proteases (α1-ATT), markers of endogenous intoxication (midmolecular peptides, nitrogen oxide), growth of general phospholipids', thereby reducing activity of inflammatory process and stopping it for 5th day of the postoperative period.