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Ostroumova O.D.

Russian Medical Academy of Continuous Professional Education

Butorov V.N.

Russian Medical Academy for Continuous Professional Education

Kochetkov A.I.

Russian Medical Academy of Continuous Professional Education

Klepikova M.V.

Russian Medical Academy for Continuous Professional Education

Golovina O.V.

Russian Medical Academy for Continuous Professional Education

Telmisartan combined with moxonidine in the treatment of arterial hypertension in obese patients

Authors:

Ostroumova O.D., Butorov V.N., Kochetkov A.I., Klepikova M.V., Golovina O.V.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2020;13(5): 452‑458

DOI: 10.17116/kardio202013051452

Views: 21285

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Table of contents

TELMISARTAN COMBINED WITH MOXONIDINE IN THE TREATMENT OF ARTERIAL HYPERTENSION IN OBESE PATIENTS
TELMISARTAN COMBINED WITH MOXONIDINE IN THE TREATMENT OF ARTERIAL HYPERTENSION IN OBESE PATIENTS

To cite this article:

Ostroumova OD, Butorov VN, Kochetkov AI, Klepikova MV, Golovina OV. Telmisartan combined with moxonidine in the treatment of arterial hypertension in obese patients. Russian Journal of Cardiology and Cardiovascular Surgery. 2020;13(5):452‑458. (In Russ.)
https://doi.org/10.17116/kardio202013051452

Подписка 2025-2 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
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Overweight or obese are observed in 60% of patients with arterial hypertension (AH) that increases cardiovascular risk. According to the current guidelines, these patients are needed to prescribe a combination of two antihypertensive drugs as a starting therapy. In this clinical case, telmisartan with moxonidine were used in a patient with hypertension, obesity, dyslipidemia and impaired glucose tolerance. High antihypertensive effectiveness of this combination was confirmed by 24-houir blood pressure monitoring. Literature data on the beneficial effect of telmisartan on the risk of cardiovascular complications are presented. Unlike other angiotensin II receptor blockers, telmisartan activates PPAR-γ receptors that improves glucose and lipid metabolism. Moxonidine increases tissue sensitivity to insulin in patients with overweight, insulin resistance and impaired glucose metabolism. Co-administration of moxonidine and telmisartan is one of the possible strategies for antihypertensive therapy in patients with hypertension and obesity.

Keywords:

arterial hypertension
obesity
antihypertensive therapy
telmisartan
moxonidine

Authors:

Ostroumova O.D.

Russian Medical Academy of Continuous Professional Education

Butorov V.N.

Russian Medical Academy for Continuous Professional Education

Kochetkov A.I.

Russian Medical Academy of Continuous Professional Education

Klepikova M.V.

Russian Medical Academy for Continuous Professional Education

Golovina O.V.

Russian Medical Academy for Continuous Professional Education

Received:

30.07.2020

Accepted:

19.08.2020

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