Aim — to generalize an experience of open surgical treatment of supra-aortic vessels aneurysms. Material and methods. Surgical outcomes in 25 patients with extracranial and extrathoracic supra-aortic vessels aneurysms were analyzed. Aneurysms of carotid arteries and their branches were diagnosed in 15 (60%) patients, subclavian arteries — in 6 (24%) cases, vertebral arteries — in 4 (16%) cases. Aneurysms of internal and common carotid arteries were observed in 6 and 5 cases, respectively. There were 4 posttraumatic and 2 degenerative —dysplastic aneurysms. Two patients had arteriovenous fistulas followed by venous aneurysm (temporal, parietal and occipital branches). Subclavian aneurysms were located in II and III segments in 4 and 3 cases, respectively. All four vertebral aneurysms were post-traumatic. Only one aneurysm was located before bone channel while other 3 patients had injury within vertebral canal. Results. Surgery included partial aneurysm resection with or without vascular repair. Restored blood flow after aneurysm repair was observed in 17 (68%) cases while ligation was performed in 8 (32%) patients. Common carotid artery ligation was performed only in 1 case due to ICA aneurysm within bone channel. In all other cases vertebral arteries (n=3) and branches of external carotid artery (n=5) were ligated. Direct or lateral vascular suture was applied only in 6 cases due to severe morphological changes of vascular wall. In 10 patients blood flow was restored via bypass or replacement with synthetic prosthesis (autovein) due to large diastase after aneurysm resection. Postoperative bleeding occurred in one case. In four cases n. hypoglosus paresis (n=2) and lymphorrhoea (n=2) were observed. All nonspecific complications were eliminated by conservative methods. There were no lethal outcomes. Conclusion. All types of operations aimed at blood flow restoration may be applied. The choice of surgery depends on aneurysm dimensions, vascular state beyond the aneurysm, defect dimensions after aneurysm removal.