Aim — the objective of the present study was to evaluate the safety and clinical effectiveness of two classes of the compression hosiery products used for the treatment of chronic venous insufficiency and varicose veins and to estimate the patients’ compliance with the prescribed mode of their application. Material and methods. Two groups of female patients were formed each comprising 15 women at the age from 18 to 60 years with the diagnosis of varicose disease of the lower extremities (CEAР class C1—C3). All of them received compression therapy during 12 weeks following sclerotherapy. Those of group 1 were treated with the use of the class 2 compression golf socks while the patients of group 2 wore class 2 compression stockings. A phlebologist evaluated the clinical, instrumental and ultrasound characteristics of the effectiveness of the treatment at the time of the scheduled visits. Each patient kept the diary to record the severity of chronic venous insufficiency symptoms, the subjective assessment of the results of the treatment, and the consumer qualities of the compression products. Results. At the completion of the course of compression therapy, the patients of the two groups showed a statistically significant reduction in the circumference of the ankle as well as a statistically significant increase of the linear velocity of blood flow in the common femoral vein which suggested the regression of the instrumental criteria for chronic diseases of veins. The subjective evaluation of the consumer properties of the compression products was similar in both groups and amounted, on the average, to 1.5—1.8 points of the 2 possible. No adverse reactions have been documented. Conclusion. The results of physical, instrumental, and subjective evaluations of the safety and effectiveness of the application of the therapeutic compression products of the above two classes give evidence that they can be recommended for wearing by the patients presenting with CEAР class C1—C3 varicose disease of the lower extremities including those who had undergone sclerotherapy.