Hyperpigmentation and telangiectatic matting are frequent adverse events after sclerotherapy in C1 patients. Venous specialists need to identify the risk factors of these adverse events.
OBJECTIVE. T
O identify the risk factors predisposing to persistent hyperpigmentation and telangiectatic matting after sclerotherapy in C1 patients.
MATERIAL AND METHODS
A database of 72 C1 patients who undergone sclerotherapy were assessed. The analysis included the following variables: age, body mass index (BMI), duration of the disease, number of sclerotherapy procedures, amount of sclerosing agent used, prolonged compression. Long-term compression implied wearing compression hosiery for 3 days after each procedure, as well as for at least 5 days throughout 4 months after the first procedure. In other cases, patients used compression only for 3 days after each sclerotherapy procedure. Class 2 stockings were used for compression.
RESULTS
After 4 months, hyperpigmentation and telangiectatic matting persisted in 12 (16.7%) and 7 (9.7%) patients, respectively. Prolonged post-procedural compression was used by 2 (16.7%) patients with persisted hyperpigmentation and 34 (57.7%) patients without hyperpigmentation (p=0.012). One (14%) patient with persisted telangiectatic matting wore compression stockings for a long time while 35 (58%) patients with this complication used short-term compression (p=0.107). Mean BMI was 25.2±5.4 kg/m2 in patients with hyperpigmentation and 22.2±3.2 kg/m2 in those without hyperpigmentation (p=0.089). In patients with and without persisted telangiectatic matting, BMI was 25.2±4.5 and 22.4±3.6 kg/m2, respectively. The only found risk factor that had an impact on persistence of hyperpigmentation and teleangiectatic matting was prolonged compression therapy in the post–procedural period — 0.09 (95% CI: 0.01—0.63; p=0.015) for hyperpigmentation and 0.09 (95% CI: 0.01—1.0; p=0.05) for telangiectatic matting.
CONCLUSIONS
The risk of persistent hyperpigmentation and telangiectatic matting after sclerotherapy in C1 patients is significantly reduced by prolonged wearing of compression stockings after treatment.
