Aim — the objective of the present article was to report the results of the treatment of the patients presenting with chronic venous diseases given in the framework of the specialized phlebological care system. Material and methods. The authors present information about 555 patients with chronic venous diseases included in the database of the prospective observational study SPECTRUM. All the patients were examined three times with an interval of one year. The study group was comprised of 435 (78.4%) women and 129 (21.6%) men at the age varying from 15 to 85 (median 46) years. Each examination included evaluation of objective and subjective clinical signs and symptoms, duplex ultrasound, and diagnostics based on the CEAP classification. The treatment was followed by the assessment of the patients’ compliance with the prescribed therapeutic regime. Results and discussion. The frequency of reticular varicosis, varicose veins, oedema, lipodermatosclerosis, eczema/dermatitis, and trophic ulcers significantly decreased during the first year. Only the frequency of varicose veins continued to decrease during the second year. No changes in the frequency of hyperpigmentation were documented throughout the study period. The frequency of subjective clinical symptoms decreased significantly during the first year. Thereafter, the positive dynamics of the majority of the symptoms persisted during the remaining periods. Complications of chronic venous diseases were observed in 22(4%) and 5 (0.9%) patients during the first and second years respectively. 32.3 and 55.2% patients to whom either sclerotherapy or the surgical intervention was prescribed based on the results of the primary and secondary examination respectively refused to follow these recommendations. At the same time, only 4.6 and 7.3% of the patients refused to wear the compression stockings and to use venoactive agents respectively. However, the rate of non-compliance with the prescribed pharmacotherapy and compression treatment amounted to 34.4 and 24.8% respectively. Conclusion. The Russian patients presenting with chronic venous diseases demonstrate poor compliance with the treatment protocols. Nevertheless, the effectiveness of specialized phlebological care in Russia is on the whole rather high. The clinical results of the treatment in the majority of cases can be described as good or excellent.