Aim. The objective of the present study was to evaluate the influence of vulvar, vaginal, and perineal vein dilatation on the clinical course and outcome of pregnancy and labor. Material and methods. The study group included 64 pregnant women presenting with varicose veins of vulva, vagina, and perineum, the control group was comprised of 64 pregnant women free from this pathology. In the study group, 15 (23.4%) patients had vulvar vein dilatation, 23 (35.9%) women had vaginal vein dilatation, and 18 (28.1%) women had perineal vein dilatation. Combined vaginal, vulvar, and perineal vein dilatation was diagnosed in 8 (12.5%) women of this group. The frequency of gynecological diseases among the women of the study group was higher than in the control group (98.4 and 21.9% respectively). Gestational complications in the study group were dominated by placental insufficiency that was diagnosed in the study group 13 times as frequently as in the control one. Almost one quarter (26.6%) of the women in the study group were at risk of miscarriage compared with 9.4% among the controls (a 2.8-fold difference). Each fifths woman (18.75%) in the study group experienced fetal growth retardation totally absent in the control group. Hydramnion occurred in 17.19% and only 1.6% of the patients in the study and control groups respectively. Each sixth woman in the study group exhibited signs of gestosids. Only one patient of the control group developed oedematous gestosis. Vaginal delivery occurred in 53 (82.8%) women of the study group, with 11 (17.2%) giving birth by cesarean section. In the control group, vaginal delivery took place in 92.2% of the women compared with 7.8% giving abdominal birth. Complications of pregnancy occurred in all the women of the study group and only in one third of them in the control one. Conclusion. Gynecological diseases concomitant with other extragenital pathology as well as pregnancy complications more frequently occurred in women with vulvar and perineal varicose veins.