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Ludwig K.

Klinikum Südstadt Rostock

Schneider-Koriath S.

Klinikum Südstadt Rostock

Bernhardt J.

Klinikum Südstadt Rostock

Current data of evidence-based medicine on laparoscopic gastrectomy for gastric cancer

Authors:

Ludwig K., Schneider-Koriath S., Bernhardt J.

More about the authors

Journal: Endoscopic Surgery. 2022;28(5): 52‑62

DOI: 10.17116/endoskop20222805152

Read: 2272 times

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Table of contents

CURRENT DATA OF EVIDENCE-BASED MEDICINE ON LAPAROSCOPIC GASTRECTOMY FOR GASTRIC CANCER
CURRENT DATA OF EVIDENCE-BASED MEDICINE ON LAPAROSCOPIC GASTRECTOMY FOR GASTRIC CANCER

To cite this article:

Ludwig K, Schneider-Koriath S, Bernhardt J. Current data of evidence-based medicine on laparoscopic gastrectomy for gastric cancer. Endoscopic Surgery. 2022;28(5):52‑62. (In Russ.)
https://doi.org/10.17116/endoskop20222805152

Подписка 2026 Эндоскопическая хирургия (Endoscopic Surgery)
МСФ на ЯМ
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Abstract:

The following study is a systematically review of the current evidence of laparoscopic distal and total gastrectomy in comparison to open surgery. A systematic search of EMBASE and Pubmed was conducted. Out of 1.034 hits a total of 257 randomized (RCT) and non-randomized (non-RCT) studies fulfilled criteria to compare feasibility, intra- and postoperative outcome, oncological quality (R0, lymphnode harvest), morbidity and mortality and the oncological long-term outcome between laparoscopic vs. open gastrectomy for early (EGC) and advanced (AGC) gastric cancer. For EGC and laparoscopic distal resection (LDG) and total gastrectomy (LTG) a total of 10 RCT and 6 non-RCT, including 4.329 patients (lap. 2.010 vs. open 2.319) were selected. On high evidence level there is no significant difference in terms of feasibility, intraoperative outcome and quality, mortality and long-term oncological outcome compared to open surgery. Patients after LDG and LTG showed a significant faster recovery and lower morbidity. In contrast, operative time for LDG and LTG was significant longer than that for ODG and OTG. For distal AGC and LDG totally 6 RCT, including 2.806 patients (LDG 1.410 vs ODG 1.369) benefits similar high evidence and results. The Evidence for LTG in cases of AGC is quiet lower. Currently only 6 non-RCT, including 1.090 patients (LTG 539 vs OTG 551) are available and showed similar results to LDG. High quality RCT’s are further necessary. Laparoscopic gastrectomy shows better recovery and oncological equivalence in comparison to open gastrectomy.

Keywords:

laparoscopic gastrectomy
gastrectomy
gastric cancer
a systematic review

Authors:

Ludwig K.

Klinikum Südstadt Rostock

Schneider-Koriath S.

Klinikum Südstadt Rostock

Bernhardt J.

Klinikum Südstadt Rostock

Received:

15.02.2022

Accepted:

10.03.2022

Close metadata

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