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Ludwig K.

Klinikum Südstadt Rostock

Schneider-Koriath S.

Klinikum Südstadt Rostock

Bernhardt J.

Klinikum Südstadt Rostock

Current data of evidence-based medicine on laparoscopic gastrectomy for gastric cancer

Authors:

Ludwig K., Schneider-Koriath S., Bernhardt J.

More about the authors

Journal: Endoscopic Surgery. 2022;28(5): 52‑62

DOI: 10.17116/endoskop20222805152

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CURRENT DATA OF EVIDENCE-BASED MEDICINE ON LAPAROSCOPIC GASTRECTOMY FOR GASTRIC CANCER
CURRENT DATA OF EVIDENCE-BASED MEDICINE ON LAPAROSCOPIC GASTRECTOMY FOR GASTRIC CANCER

To cite this article:

Ludwig K, Schneider-Koriath S, Bernhardt J. Current data of evidence-based medicine on laparoscopic gastrectomy for gastric cancer. Endoscopic Surgery. 2022;28(5):52‑62. (In Russ.)
https://doi.org/10.17116/endoskop20222805152

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The following study is a systematically review of the current evidence of laparoscopic distal and total gastrectomy in comparison to open surgery. A systematic search of EMBASE and Pubmed was conducted. Out of 1.034 hits a total of 257 randomized (RCT) and non-randomized (non-RCT) studies fulfilled criteria to compare feasibility, intra- and postoperative outcome, oncological quality (R0, lymphnode harvest), morbidity and mortality and the oncological long-term outcome between laparoscopic vs. open gastrectomy for early (EGC) and advanced (AGC) gastric cancer. For EGC and laparoscopic distal resection (LDG) and total gastrectomy (LTG) a total of 10 RCT and 6 non-RCT, including 4.329 patients (lap. 2.010 vs. open 2.319) were selected. On high evidence level there is no significant difference in terms of feasibility, intraoperative outcome and quality, mortality and long-term oncological outcome compared to open surgery. Patients after LDG and LTG showed a significant faster recovery and lower morbidity. In contrast, operative time for LDG and LTG was significant longer than that for ODG and OTG. For distal AGC and LDG totally 6 RCT, including 2.806 patients (LDG 1.410 vs ODG 1.369) benefits similar high evidence and results. The Evidence for LTG in cases of AGC is quiet lower. Currently only 6 non-RCT, including 1.090 patients (LTG 539 vs OTG 551) are available and showed similar results to LDG. High quality RCT’s are further necessary. Laparoscopic gastrectomy shows better recovery and oncological equivalence in comparison to open gastrectomy.

Keywords:

laparoscopic gastrectomy
gastrectomy
gastric cancer
a systematic review

Authors:

Ludwig K.

Klinikum Südstadt Rostock

Schneider-Koriath S.

Klinikum Südstadt Rostock

Bernhardt J.

Klinikum Südstadt Rostock

Received:

15.02.2022

Accepted:

10.03.2022

List of references:

  1. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394-424. 
  2. Kitano S, Iso Y, Moriyama M, Sugimachi K. Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc. 1994;4:146-148. 
  3. OCEBM Levels of Evidence — Centre for Evidence-Based Medicine (CEBM), University of Oxford. https://www.cebm.ox.ac.uk/resources/levels-of-evidence/ocebm-levels-of-evidence.
  4. Möhler M, Al-Batran SE, Andus T, et al. (2019) S3-Leitlinie Diagnostik und Therapie der Adenokarzinome des Magens und ösophagogastralen Übergangs. Version 2.0, AWMF 032/009OL. www.awmf.org/leitlinien/detail/II/032-009OL.html.
  5. Mönig S, Ott, K, Gockel I, et al. S3-Leitlinie Magenkarzinom — Diagnostik und Therapie der Adenokarzinome des Magens und ösophagogastralen Übergangs. Version 2.0. Chirurg. 2020;91:37-40. 
  6. Ludwig K, Möller D, Bernhardt J. Chirurgische Strategie bei Frühkarzinomen des Magens. Chirurg. 2018;89:347-357. 
  7. Kim MG, Kim BS, Kim TH, et al. The effects of laparoscopic assisted total gastrectomy on surgical outcomes in the treatment of gastric cancer. J Korean Surg Soc. 2011;80:245-250. 
  8. Mochiki E, Toyomasu Y, Ogata K, et al. Laparoscopically assisted total gastrectomy with lymph node dissection for upper and middle gastric cancer. Surg Endosc. 2008;22:1997-2002.
  9. Park YK, Yoon HM, Kim YW, et al. Laparoscopy-assisted versus open D2 distal gastrectomy for advanced gastric cancer: results from a randomized phase II multicenter clinical trial (COACT 1001). Ann Surg. 2018;267:638-645. 
  10. Usui S, Yoshida T, Ito K, et al. Laparoscopy-assisted total gastrectomy for early gastric cancer: comparison with conventional open total gastrectomy. Surg Laparosc Endosc Percutan Tech. 2005;15:309-314. 
  11. Katai H, Mizusawa J, Katayama H, et al. Short-term surgical outcomes from a phase III study of laparoscopy-assisted versus open distal gastrectomy with nodal dissection for clinical stage IA/IB gastric cancer: Japan Clinical Oncology Group Study JCOG0912. Gastric Cancer. 2017;20:699-708. 
  12. Kim HH, Han SU, Kim MC, et al. Prospective randomized controlled trial (phase III) to comparing laparoscopic distal gastrectomy with open distal gastrectomy for gastric adenocarcinoma (KLASS 01). J Korean Surg Soc. 2013;84:123-130. 
  13. Hayashi H, Ochiai T, Shimada H, Gunji Y. Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer. Surg Endosc. 2005;19:1172-1176.
  14. Kim YW, Baik YH, Yun YH, et al. Improved quality of life outcomes after laparoscopy-assisted distal gastrectomy for early gastric cancer: results of a prospective randomized clinical trial. Ann Surg. 2008;248:721-727. 
  15. Kitano S, Shiraishi N, Fujii K, et al. A randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: an interim report. Surgery. 2002;131:S306-311. 
  16. Lee JH, Han HS, Lee JH. A prospective randomized study comparing open vs laparoscopy-assisted distal gastrectomy in early gastric cancer: early results. Surg Endosc. 2005;19:168-173. 
  17. Sakuramoto S, Yamashita K, Kikuchi S, et al. Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial. Surg Endosc. 2013;27:1695-1705.
  18. Takiguchi S, Fujiwara Y, Yamasaki M, et al. Laparoscopy-assisted distal gastrectomy versus open distal gastrectomy. A prospective randomized single-blind study. World J Surg. 2013;37:2379-2386.
  19. Yamashita K, Sakuramoto S, Kikuchi S, et al. Laparoscopic versus open distal gastrectomy for early gastric cancer in Japan: long-term clinical outcomes of a randomized clinical trial. Surg Today. 2016;46:741-749. 
  20. Best LMJ, Mughal M, Gurusamy KS. Laparoscopic versus open gastrectomy for gastric cancer. Cochrane Database Syst Rev. 2016;3:CD011389. https://doi.org/10.1002/14651858.CD011389.pub2
  21. Sakamoto T, Fujiogi M, Matsui H, et al. Short-term outcomes of laparoscopic and open total gastrectomy for gastric cancer: a nationwide retrospective cohort analysis. Ann Surg Oncol. 2020;27:518-526. 
  22. Jeong O, Jung MR, Kim GY, et al. Comparison of short-term surgical outcomes between laparoscopic and open total gastrectomy for gastric carcinoma: case-control study using propensity score matching method. J Am Coll Surg. 2013;216:184-191. 
  23. Kawamura H, Yokota R, Homma S, Kondo Y. Comparison of invasiveness between laparoscopy-assisted total gastrectomy and open total gastrectomy. World J Surg. 2009;33:2389-2395.
  24. Lee JH, Nam BH, Ryu KW, et al. Comparison of outcomes after laparoscopy-assisted and open total gastrectomy for early gastric cancer. BJS. 2015;102:1500-1505.
  25. Liu F, Huang C, Xu Z, et al. Morbidity and mortality of laparoscopic vs open total gastrectomy for clinical stage I gastric cancer: the CLASS02 multicenter randomized clinical trial. JAMA Oncol. 2020. https://doi.org/10.1001/jamaoncol.2020.3152.
  26. Hyung WJ, Yang HK, Han SU, et al. A feasibility study of laparoscopic total gastrectomy for clinical stage I gastric cancer: a prospective multi-center phase II clinical trial, KLASS 03. Gastric Cancer. 2019;22:214-222. 
  27. Kinoshita T, Uyama I, Terashima M, et al. Long-term outcomes of laparoscopic versus open surgery for clinical stage II/III gastric cancer: a multicenter cohort study in Japan (LOC-A Study). Ann Surg. 2019;269:887-894. 
  28. Hiki N, Katai H, Mizusawa J, et al. Long-term outcomes of laparoscopy-assisted distal gastrectomy with suprapancreatic nodal dissection for clinical stage I gastric cancer: a multicenter phase II trial (JCOG0703). Gastric Cancer. 2018;21:155-161. 
  29. Kim HH, Han SU, Kim MC, et al. Effect of laparoscopic distal gastrectomy vs open distal gastrectomy on long-term survival among patients with stage I gastric gancer: the KLASS-01 randomized clinical trial. JAMA Oncol. 2019;5:506-513. 
  30. Zeng YK, Yang ZL, Peng JS, et al. Laparoscopy-assisted versus open distal gastrectomy for early gastric cancer: evidence from randomized and nonrandomized clinical trials. Ann Surg. 2012;256:39-52. 
  31. Kim W, Kim HH, Han SU, et al. Decreased morbidity of laparoscopic distal gastrectomy compared with open distal gastrectomy for stage I gastric cancer: short-term outcomes from a multicenter randomized controlled trial (KLASS-01). Ann Surg. 2016;263:28-35. 
  32. Hu Y, Huang C, Sun Y, et al. Morbidity and Mortality of Laparoscopic Versus Open D2 Distal Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial. J Clin Oncol. 2016;34:1350-1357.
  33. Hyung WJ, Yang HK, Park YK, et al. Long-term outcomes of laparoscopic distal gastrectomy for locally advanced gastric cancer: the KLASS-02-RCT randomized clinical trial. J Clin Oncol. 2020;38(28):3304-3313. https://doi.org/10.1200/JCO.20.01210
  34. Inaki N, Etoh T, Ohyama T, et al. A multi-institutional, prospective, phase II feasibility study of laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for locally advanced gastric cancer (JLSSG0901). World J Surg. 2015;39:2734-2741.
  35. Huscher CGS, Mingoli A, Sgarzini G, et al. Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial. Ann Surg. 2005;241:232-237. 
  36. Wang Z, Xing J, Cai J, et al. Short-term surgical outcomes of laparoscopy-assisted versus open D2 distal gastrectomy for locally advanced gastric cancer in North China: a multicenter randomized controlled trial. Surg Endosc. 2019;33:33-45. 
  37. Yu J, Huang C, Sun Y, et al. Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer: the CLASS-01 randomized clinical trial. JAMA. 2019;321:1983-1992.
  38. Ludwig K, Schneider-Koriath S, Scharlau U, et al. Laparoskopische vs. konventionell-offene D2-Gastrektomie bei Magenkarzinom: eine Matched-Pair-Analyse. Zentralbl Chir. 2018;143(2):145-154. 
  39. Ramagem CAG, Linhares M, Lacerda CF, et al. Comparison of laparoscopic total gastrectomy and laparotomic total gastrectomy for gastric cancer. ABCD Arq Bras Cir Dig. 2015;28:65-69. 
  40. Siani LM, Ferranti F, De Carlo A. Quintiliani A Completely laparoscopic versus open total gastrectomy in stage I-III/C gastric cancer: safety, efficacy and five-year oncologic outcome. Minerva Chir. 2012;67:319-326. 
  41. Topal B, Leys E, Ectors N, et al. Determinants of complications and adequacy of surgical resection in laparoscopic versus open total gastrectomy for adenocarcinoma. Surg Endosc. 2008;22:980-984. 
  42. Cai J, Wei D, Gao CF, et al. A prospective randomized study comparing open versus laparoscopy-assisted D2 radical gastrectomy in advanced gastric cancer. Dig Surg. 2011;28:331-337. 
  43. Cui M, Li Z, Xing J, et al. A prospective randomized clinical trial comparing D2 dissection in laparoscopic and open gastrectomy for gastric cancer. Med Oncol. 2015;32:241. 
  44. Bo T, Peiwu Y, Feng Q, et al. Laparoscopy-assisted vs. open total gastrectomy for advanced gastric cancer: long-term outcomes and technical aspects of a case-control study. J Gastrointest Surg. 2013;17:1202-1208.
  45. Chen XZ, Wang SY, Wang YS, et al. Comparisons of short-term and survival outcomes of laparoscopy-assisted versus open total gastrectomy for gastric cancer patients. Oncotarget. 2017;8:52366-52380.
  46. Du J, Zheng J, Li Y, et al. Laparoscopy-assisted total gastrectomy with extended lymph node resection for advanced gastric cancer-reports of 82 cases. Hepato-Gastroenterology. 2010;57:1589-1594.
  47. Lu Y, Jiang B, Liu T. Laparoscopic versus open total gastrectomy for advanced proximal gastric carcinoma: a matched pair analysis. J BUON. 2016;21:903-908. 
  48. Shu B, Lei S, Li F, et al. Laparoscopic total gastrectomy compared with open resection for gastric carcinoma: a case-matched study with long-term follow-up. J BUON. 2016;21:101-107. 
  49. Wu H, Li W, Chen G, et al. Outcome of laparoscopic total gastrectomy for gastric carcinoma. J BUON. 2016;21:603-608. 
  50. Ziyu li, Shan F, Ying XJ, et al. Assessment of laparoscopic distal gastrectomy after neoadjuvant chemotherapy for locally advanced gastric cancer. A randomized clinical trial. JAMA Surg. 2019;154:1093-1101.
  51. Zheng XY, Pan Y, Chen K, et al. Comparison of intracorporeal and extracorporeal esophagojejunostomy after laparoscopic total gastrectomy for gastric cancer: a meta-analysis based on short-term outcomes. Chin Med J (Engl). 2018;131:713-720. 
  52. Sica GS, Iaculli E, Biancone L, et al. Comparative study of laparoscopic vs open gastrectomy in gastric cancer management. World J Gastroenterol. 2011;17:4602-4606.
  53. Inokuchi M, Otsuki S, Fujimori Y, et al. Systematic review of anastomotic complications of esophagojejunostomy after laparoscopic total gastrectomy. World J Gastroenterol. 2015;21:9656-9665.
  54. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-560. 
  55. Mamidanna R, Almoudaris AM, Bottle A, et al. National outcomes and uptake of laparoscopic gastrectomy for cancer in England. Surg Endosc. 2013;27:3348-3358.
  56. Brenkman HJF, Gisbertz SS, Slaman AE, et al Postoperative outcomes of minimally invasive gastrectomy versus open gastrectomy during the early introduction of minimally invasive gastrectomy in the Netherlands: a population-based cohort study. Ann Surg. 2017;266:831-838. 
  57. Yoshida K, Honda M, Kumamaru H, et al. Surgical outcomes of laparoscopic distal gastrectomy compared to open distal gastrectomy: aretrospective cohort study based on nationwide registry database in Japan. Ann Gastroenterol Surg. 2017;2:55-64. 
  58. Kodera Y, Yoshida K, Kumamaru H, et al. Introducing laparoscopic total gastrectomy for gastric cancer in general practice: a retrospective cohort study based on a nationwide registry database in Japan. Gastric Cancer. 2019;22:202-213. 
  59. Dulucq JL, Wintringer P, Stabilini C, et al Laparoscopic and open gastric resections for malignant lesions: a prospective comparative study. Surg Endosc. 2005;19:933-938. 
  60. Scatizzi M, Kröning KC, Lenzi E, et al. Laparoscopic versus open distal gastrectomy for locally advanced gastric cancer: a case-control study. Updates in Surg. 2011;63:17-23. 
  61. Orsenigo E, Di Palo S, Tamburini A, Staudacher C. Laparoscopy-assisted gastrectomy versus open gastrectomy for gastric cancer: a monoinstitutional Western center experience. Surg Endosc. 2011;25:140-145. 
  62. Sarela AI. Entirely laparoscopic radical gastrectomy for adenocarcinoma: lymph node yield and resection margins. Surg Endosc. 2009;23:153-160. 
  63. Cianchi F, Qirici E, Trallori G, et al. Totally laparoscopic versus open gastrectomy for gastric cancer: a matched cohort study. J Laparoendosc Adv Surg Tech A. 2013;23:117-122. 
  64. An JY, Heo G-U, Cheong J-H, et al. Assessment of open versus laparoscopy-assisted gastrectomy in lymph node-positive early gastric cancer: a retrospective cohort analysis. J Surg Oncol. 2010;102:77-81. 
  65. Kelly KJ, Selby L, Chou JF, et al. Laparoscopic versus open gastrectomy for gastric adenocarcinoma in the West: a case-control study. Ann Surg Oncol. 2015;22:3590-3596.
  66. Raakow J, Denecke C, Chopra S, et al. Laparoskopische versus offene Gastrektomie bei fortgeschrittenem Magenkarzinom. Chirurg. 2020;91:252-261. 
  67. Allemani C, Matsuda T, Di Carlo V, et al. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018;391:1023-1075.
  68. Strong VE, Song KY, Park CH, et al. Comparison of gastric cancer survival following R0 resection in the United States and Korea using an internationally validated nomogram. Ann Surg. 2010;251:640-646. 
  69. Fang C, Hua J, Li J, et al. Comparison of long-term results between laparoscopy-assisted gastrectomy and open gastrectomy with D2 lymphadenectomy for advanced gastric cancer. Am J Surg. 2014;208:391-396. 
  70. Shinohara T, Satoh S, Kanaya S, et al. Laparoscopic versus open D2 gastrectomy for advanced gastric cancer: a retrospective cohort study. Surg Endosc. 2013;27:286-294. 

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