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Kaibysheva V.O.

N.I. Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №31, Moscow, Russia

Zharova M.E.

Pirogov Russian National Research Medical University, Moscow, Russia;
Scientific Research Institute of Healthcare Organizatiob and Medical Management, Moscow, Russia

Filimendikova K.Yu.

Yaroslavl State Medical University, Yaroslavl, Russia

Nikonov E.L.

FGBU "Poliklinika #1" Upravleniia delami Prezidenta RF

Human Microbiome: age-related changes and functions

Authors:

Kaibysheva V.O., Zharova M.E., Filimendikova K.Yu., Nikonov E.L.

More about the authors

Journal: Russian Journal of Evidence-Based Gastroenterology. 2020;9(2): 42‑55

DOI: 10.17116/dokgastro2020902142

Views: 46324

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To cite this article:

Kaibysheva VO, Zharova ME, Filimendikova KYu, Nikonov EL. Human Microbiome: age-related changes and functions. Russian Journal of Evidence-Based Gastroenterology. 2020;9(2):42‑55. (In Russ.)
https://doi.org/10.17116/dokgastro2020902142

Подписка 2025 (Russian Journal of Evidence-Based Gastroenterology)
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Objective. To analyse information about age-related changes of the microbiome and its most important functions. Key points. Significant interest to the human microbiome in recent decades was determined by the development of new diagnostic methods, including 16S ribosomal RNA sequencing, whole-genome sequencing, chromatospectrometry, and others. These methods have significantly improved understanding of the role of intestinal microbiota and its unique metabolites in regulation of various physiological functions, including colonization resistance of the mucous membranes, metabolism, development, and homeostasis of immune and nervous systems. Conclusion. Despite a large amount of available information about the human microbiome, an understanding of its function in the human body is still far from perfect, which necessitates further research.

Keywords:

microbiota
microbiome
fecal microbiota transplantation
probiotics

Authors:

Kaibysheva V.O.

N.I. Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №31, Moscow, Russia

Zharova M.E.

Pirogov Russian National Research Medical University, Moscow, Russia;
Scientific Research Institute of Healthcare Organizatiob and Medical Management, Moscow, Russia

Filimendikova K.Yu.

Yaroslavl State Medical University, Yaroslavl, Russia

Nikonov E.L.

FGBU "Poliklinika #1" Upravleniia delami Prezidenta RF

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