Angiomatoid fibrous histiocytoma: a literature review and a report of two cases

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Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of intermediate malignancy potential, which predominantly affects children and young adults. This paper describes two cases of AFH, as well as a review of literature during 1979 to 2021. It gives data on the epidemiology, clinical features, diagnosis, and genetic characteristics of AFH.

Keywords:

angiomatoid fibrous histiocytoma

ALK

SOX9

IL-6

Authors:

Fedorova A.S.

Lomonosov Moscow State University

ORCID: 0000-0002-4699-1730

Sidorov I.V.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

ORCID: 0000-0001-8578-6572

Konovalov D.M.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology;
Russian Medical Academy of Continuous Professional Education

ORCID: 0000-0001-7732-8184

Received:

19.04.2021

Accepted:

28.06.2021

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