Классификация эпителиальных опухолей желудка ВОЗ 2019 г., 5-е издание

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Классификация эпителиальных новообразований желудка 2019 г. частично изменена по сравнению с изданием 2010 г.: выделены новые гистологические подтипы дисплазий (зубчатая дисплазия, дисплазия желудочных ямок/крипт), изменилась структура классификации доброкачественных новообразований (термин аденоматозный полип вновь вводится в обращение и представляет собой группу доброкачественных опухолей, ранее относимых к аденомам желудочного типа), раздел злокачественных эпителиальных опухолей расширен за счет карциномы из париетальных клеток, микропапиллярной и мукоэпидермоидной карцином, рака из клеток Панета. Факторы риска рака желудка разделены на две группы в зависимости от уровня доказательности их участия в канцерогенезе. Наиболее значимыми признаны: выявленная инфекция Helicobacter pylori, работа, связанная с производством резины, курение табака, рентгеновское и гамма-излучение. Изменены подходы к градации раков желудка по степени дифференцировки: подчеркивается предпочтительное использование двухступенчатой градации (low grade/ high grade). Нововведения также коснулись стадирования рака желудка. Раздел, посвященный нейроэндокринным опухолям, существенных изменений не претерпел. В целом новая классификация содержит более подробные данные по каждому из разделов, однако она не является интуитивно понятной. Пункты классификационной таблицы не соответствуют названиям разделов в тексте, что затрудняет понимание структуры и навигацию.

Ключевые слова:

классификация ВОЗ

дисплазия/интраэпителиальная неоплазия желудка

рак желудка

аденоматозный полип

аденома желудка кишечного типа

стадирование рака желудка

градация рака желудка

молекулярная классификация рака желудка

Авторы:

Данилова Н.В.

ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»

Олейникова Н.А.

ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»

Мальков П.Г.

ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России

Даты поступления:

10.02.2020

Даты принятия в печать:

20.04.2020

Список литературы:

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