Антимикробная профилактика и предотвращение инфекции области хирургического вмешательства у взрослых пациентов кардиохирургического профиля

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Инфекция области хирургического вмешательства (ИОХВ) занимает важное место в структуре внутрибольничных инфекций. Хирургическая антимикробная профилактика (АМП) рутинно используется в кардиохирургической практике для снижения частоты ИОХВ, летальности и экономических затрат. Выполнен комплексный анализ современных источников литературы, посвященных этой проблеме. Выявлено, что цефалоспорины первого поколения имеют сопоставимую эффективность по сравнению с цефалоспоринами второго и третьего поколения, гликопептиды имеют сопоставимый с цефазолином профиль безопасности и могут быть альтернативой цефалоспоринам или использоваться в составе комбинированных схем. Коррекция дозы антибиотика по массе тела и клиренсу креатинина может улучшать результаты АМП, а соблюдение фармакологических и нефармакологических протоколов является ключевым фактором профилактики ИОХВ.

Ключевые слова:

результаты

антимикробная профилактика

сердечная хирургия

инфекция области хирургического вмешательства

предотвращение инфекции

Авторы:

Степин А.В.

ГБУЗ СО «Научно-практический центр специализированных видов медицинской помощи "Уральский институт кардиологии"»

ORCID: 0000-0002-0104-2777

Дата поступления:

04.03.2023

Дата принятия в печать:

02.06.2023

Список литературы:

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