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Tsedinova Yu.B.

Sechenov First Moscow State Medical University (Sechenov University)

Churyukanov M.V.

Sechenov First Moscow State Medical University (Sechenov University);
Petrovsky Russian Scientific Center of Surgery

Zagorulko O.I.

Petrovsky National Research Center of Surgery

Medvedeva L.A.

Petrovsky National Research Center of Surgery

Yarygin I.V.

Petrovsky National Research Center of Surgery

Dombrovskaya A.V.

Petrovsky Russian Scientific Center of Surgery

Kabanova M.N.

Petrovsky National Research Center of Surgery

Neizvestnykh D.P.

Petrovsky National Research Center of Surgery

Melkonyan K.U.

Petrovsky National Research Center of Surgery

Aleksandrova E.N.

Petrovsky National Research Center of Surgery

Voropaeva V.I.

Petrovsky National Research Center of Surgery

Chronic postoperative pain in cardiac surgery: analysis of quantitative sensory testing and pain history data

Authors:

Tsedinova Yu.B., Churyukanov M.V., Zagorulko O.I., Medvedeva L.A., Yarygin I.V., Dombrovskaya A.V., Kabanova M.N., Neizvestnykh D.P., Melkonyan K.U., Aleksandrova E.N., Voropaeva V.I.

More about the authors

Journal: Russian Journal of Pain. 2025;23(1): 16‑23

DOI: 10.17116/pain20252301116

Views: 261

Downloaded: 3

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Table of contents

CHRONIC POSTOPERATIVE PAIN IN CARDIAC SURGERY: ANALYSIS OF QUANTITATIVE SENSORY TESTING AND PAIN HISTORY DATA
CHRONIC POSTOPERATIVE PAIN IN CARDIAC SURGERY: ANALYSIS OF QUANTITATIVE SENSORY TESTING AND PAIN HISTORY DATA

To cite this article:

Tsedinova YuB, Churyukanov MV, Zagorulko OI, et al. . Chronic postoperative pain in cardiac surgery: analysis of quantitative sensory testing and pain history data. Russian Journal of Pain. 2025;23(1):16‑23. (In Russ.)
https://doi.org/10.17116/pain20252301116

 
Подписка 2025-2 (Russian Journal of Pain)
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OBJECTIVE

To analyze neurophysiological profile (thresholds of temperature sensitivity and pain, pain pressure threshold), algological profile (pre-existing pain history, pain in early postoperative period, central sensitization inventory data), as well as features of surgical intervention in patients who underwent cardiac and/or aortic surgery with and without chronic postoperative pain (CPP).

MATERIAL AND METHODS

The study included 100 patients who underwent cardiac and/or aortic surgery. All patients underwent quantitative sensory testing (QST) with thermal and pressure stimulation before surgery. Patients were also questioned regarding chronic pain and completed the central sensitization inventory. In early postoperative period, patients were questioned regarding severe pain syndrome (VAS score >6). In 3—6 months after surgery, patients were interviewed regarding CPP. According to these results, patients were divided into two groups: CPSP group (30 patients) and non-CPSP group (70 patients). Statistical analysis included t-test, non-parametric Mann–Whitney U-test and Spearman’s rank correlation coefficient.

RESULTS

CPP occurred in 30% of patients. Severe early postoperative pain was more common in patients with CPP compared to the control group (p=0.0001). There was association of central sensitization with CPP (p=0.002). No significant differences in QST data and surgery time were found.

CONCLUSION

To minimize the risk of CPP and select therapy for chronic postoperative pain, clear understanding of mechanisms is necessary taking into account various aspects (psychological state, anamnestic data, sensitivity, features of sensory profile).

Keywords:

chronic postoperative pain
cardiac surgery
central sensitization
quantitative sensory testing

Authors:

Tsedinova Yu.B.

Sechenov First Moscow State Medical University (Sechenov University)

Churyukanov M.V.

Sechenov First Moscow State Medical University (Sechenov University);
Petrovsky Russian Scientific Center of Surgery

Zagorulko O.I.

Petrovsky National Research Center of Surgery

Medvedeva L.A.

Petrovsky National Research Center of Surgery

Yarygin I.V.

Petrovsky National Research Center of Surgery

Dombrovskaya A.V.

Petrovsky Russian Scientific Center of Surgery

Kabanova M.N.

Petrovsky National Research Center of Surgery

Neizvestnykh D.P.

Petrovsky National Research Center of Surgery

Melkonyan K.U.

Petrovsky National Research Center of Surgery

Aleksandrova E.N.

Petrovsky National Research Center of Surgery

Voropaeva V.I.

Petrovsky National Research Center of Surgery

Received:

21.10.2024

Accepted:

25.11.2024

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