The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Ushakov I.L.

Clinical and Diagnostic Center of «Gazprom» JSC

Potievskaya V.I.

Herzen Moscow Research Oncological Institute — Branch of the National Medical Research Center of Radiology

Comparison of different anesthetic methods for oocyte retrieval in assisted reproductive technologies

Authors:

Ushakov I.L., Potievskaya V.I.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2022;(1): 88‑101

DOI: 10.17116/anaesthesiology202201188

Read: 4210 times

Download PDF (RU)
Contact the author
Table of contents

COMPARISON OF DIFFERENT ANESTHETIC METHODS FOR OOCYTE RETRIEVAL IN ASSISTED REPRODUCTIVE TECHNOLOGIES
COMPARISON OF DIFFERENT ANESTHETIC METHODS FOR OOCYTE RETRIEVAL IN ASSISTED REPRODUCTIVE TECHNOLOGIES

To cite this article:

Ushakov IL, Potievskaya VI. Comparison of different anesthetic methods for oocyte retrieval in assisted reproductive technologies. Russian Journal of Anesthesiology and Reanimatology. 2022;(1):88‑101. (In Russ.)
https://doi.org/10.17116/anaesthesiology202201188

Подписка 2025-2 (АиР)
МСФ на ЯМ
Использование инфографики авторами научных работ
Mediasphera_Net
Close metadata
Recommended articles:
Intraoperative moni­toring of seda­tion and analgesia in patients over 70 years old in ENT surgery: a randomized prospective study. Russian Journal of Anesthesiology and Reanimatology. 2024;(4):24-31
Advi­sability of NSAID combined with central muscle rela­xant for pain syndrome after thoracoscopic surgery. Russian Journal of Anesthesiology and Reanimatology. 2024;(5):82-87
Consciousness, sleep, anesthesia. What are we thinking about? Part I. Physiology of consciousness and sleep. Russian Journal of Anesthesiology and Reanimatology. 2024;(5):96-102
Perioperative mana­gement of patients with valvular heart disease. Clinical guidelines of the All-Russian Public Orga­nization “Federation of Anesthesiologists and Reanimatologists” (2nd revi­sion, part 1). Russian Journal of Anesthesiology and Reanimatology. 2024;(6):6-22
Assi­sted reproductive technologies and the risk of placenta accreta. Russian Journal of Human Reproduction. 2024;(3):43-49
Correlation depe­ndence of tissue inhi­bitor of meta­lloproteinase-1 levels and follicular fluid morphology in patients with combined (uterine myoma and endo­metriosis) infe­rtility in the ART-programs. Russian Bulletin of Obstetrician-Gynecologist. 2024;(4):21-28
Calcium-phosphorus meta­bolism and assi­sted reproductive technologies: inte­rsection points. Russian Journal of Human Reproduction. 2024;(4):19-28
The dile­mma of mana­gement of patients with endo­metrioma and infe­rtility. Russian Journal of Human Reproduction. 2024;(4):29-37
The place of GnRH anta­gonists in modern ART programs: the possibilities of using of new drug of gani­relix. Russian Journal of Human Reproduction. 2024;(4):38-50
Regu­latory control of gestagens use in Russia in the era of indi­vidualized luteal phase support for assi­sted reproduction cycles. Russian Journal of Human Reproduction. 2024;(4):59-70

The review summarizes data on anesthetic approaches in assisted reproductive technologies for the period 2011—2021. The authors analyzed predominantly randomized national and foreign clinical trials devoted to anesthetic management of transvaginal oocyte retrieval. Peculiarities of general anesthesia, including intravenous and inhalational anesthetics, conscious sedation with propofol and short-acting opioids and regional anesthesia including neuraxial anesthesia and paracervical blockade were analyzed. We compared various anesthetic approaches regarding certain parameters: procedure time, recovery time, intensity of postoperative pain, patient satisfaction, side effects and influence on in vitro fertilization results. Data on alternative anesthetic methods in assisted reproductive technologies are given.

Keywords:

assisted reproductive technology
transvaginal oocyte retrieval
anesthesia
analgesia
sedation

Authors:

Ushakov I.L.

Clinical and Diagnostic Center of «Gazprom» JSC

Potievskaya V.I.

Herzen Moscow Research Oncological Institute — Branch of the National Medical Research Center of Radiology

Received:

26.08.2021

Accepted:

21.09.2021

List of references:

  1. Koroleva YuD, Imamieva AE, Yamshchikova TV. In vitro fertilization method — performance in Russia for 2018. Modern Science. 2021;5-4:60-64. (In Russ.).
  2. Hayes MF, Sacco AG, Savoy-Moore RT, Magyar DM, Endler GC, Moghissi KS. Effect of general anesthesia on fertilization and cleavage of human oocytes in vitro. Fertility and Sterility. 1987;48(6):975-981.  https://doi.org/10.1016/s0015-0282(16)59594-6
  3. Matsota P, Kaminioti E, Kostopanagiotou G. Anesthesia Related Toxic Effects on In Vitro Fertilization Outcome: Burden of Proof. BioMed Research International. 2015;2015:475362. https://doi.org/10.1155/2015/475362
  4. Sharma A, Borle A, Trikha A. Anesthesia for in vitro fertilization. Journal of Obstetric Anaesthesia and Critical Care. 2015;5(2):62-72.  https://doi.org/10.4103/2249-4472.165132
  5. Siristatidis C, Chrelias C, Alexiou A, Kassanos D. Clinical complications after transvaginal oocyte retrieval: a retrospective analysis. Journal of Obstetrics and Gynaecology. 2013;33(1):64-66.  https://doi.org/10.3109/01443615.2012.721818
  6. Levi-Setti PE, Cirillo F, Scolaro V, Emanuela Morenghi E, Heilbron F, Girardello D, Zannoni E, Patrizio P. Appraisal of clinical complications after 23,827 oocyte retrievals in a large assisted reproductive technology program. Fertility and Sterility. 2018;109(6):1038-1043. https://doi.org/10.1016/j.fertnstert.2018.02.002
  7. Aldrete JA. The post-anesthesia recovery score revisited. Journal of Clinical Anesthesia. 1995;7(1):89-91.  https://doi.org/10.1016/0952-8180(94)00001-k
  8. Ushakov IL, Potievskaya VI, Popov AA, Loginova EA. A Comparison of the Effects of Inhalation and Intravenous Anesthesia for Transvaginal Ovarian Puncture. Doctor.Ru. 2017;135(6):50-54. (In Russ.).
  9. Petrova MV, Potievskaia VI, Ushakov IL. Anesthetic management in clinic that specializes in assisted reproductive technologies. Doctor.Ru. 2014;96(8-1):39-41. (In Russ.).
  10. Potievskaya VI, Popov AA, Ushakov IL. Air Monitoring During Inhalation Anesthesia in In-Vitro-Fertilization Unit. Doctor.Ru. Gynecologya. 2015;112(11):22-26. (In Russ.).
  11. Vartanova IV, Korostelev YuM, Shirokov DM. Anesthesia parameters in in vitro fertilization. Vestnik anesteziologii i reanimatologii. 2021;18(1):93-102. (In Russ.). https://doi.org/10.21292/2078-5658-2021-18-1-93-102.
  12. Azmude A, Agha’amou S, Yousefshahi F, Berjis K, Mirmohammad’khani M, Sadaat’ahmadi F, Ghods K, Dabbagh A. Pregnancy outcome using general anesthesia versus spinal anesthesia for in vitro fertilization. Anesthesiology and Pain Medicine. 2013;3(2):239-242.  https://doi.org/10.5812/aapm.11223
  13. Aghaamoo S, Azmoodeh A, Yousefshahi F, Berjis K, Ahmady F, Qods K, Mirmohammadkhani M. Does Spinal Analgesia have Advantage over General Anesthesia for Achieving Success in In-Vitro Fertilization? Oman Medical Journal. 2014;29(2):97-101.  https://doi.org/10.5001/omj.2014.24
  14. Goutziomitrou E, Venetis CA, Kolibianakis EM, Bosdou JK, Parlapani A, Grimbizis G, Tarlatzis BC. Propofol versus thiopental sodium as anaesthetic agents for oocyte retrieval: a randomized controlled trial. Reproductive Biomedicine Online. 2015;31(6):752-759.  https://doi.org/10.1016/j.rbmo.2015.08.013
  15. Matsota P, Sidiropoulou T, Batistaki C, Giannaris D, Pandazi A, Krepi H, Christodoulaki K, Kostopanagiotou G. Analgesia with remifentanil versus anesthesia with propofol-alfentanil for transvaginal oocyte retrieval: a randomized trial on their impact on in vitro fertilization outcome. Middle East Journal of Anaesthesiology. 2012;21(5):685-692. 
  16. Zitta M, Mata A, Santiago G, Gomez MH, Sarmiento SCA, Avendaño C. Deleterious impact of propofol on in vitro fertilization: a prospective randomized trial. Fertility and Sterility. 2013;100(3):11.  https://doi.org/10.1016/j.fertnstert.2013.07.158
  17. Urfalıoğlu A, Arslan M, Bakacak M, Öksüz H, Boran ÖF, Öksüz G. Efficacy of bispectral index monitoring for prevention of anestheticawareness and complications during oocyte pick-up procedure. Turkish Journal of Medical Sciences. 2017;47(5):1583-1589. https://doi.org/10.3906/sag-1609-114
  18. Ramìrez-Paesano C, Fhima IB, Medina R, Urbina MT, Martínez C, Biber JL. Evaluation of Plasmatic Concentration of Propofol 2.5µg/ml by TCI using Marsh Modified Model, during oocyte retrieval for IVF in Latin-American women (Venezuelans). JBRA Assisted Reproduction. 2015;19(1):2-7.  https://doi.org/10.5935/1518-0557.20150002
  19. Liang FG, Shi YS, Ding H, Zhou W, Gu MN. [Application of subclinical doses of pentazocine and propofol in painless vaginal egg retrieval]. Nan Fang Yi Ke Da Xue Xue Bao. 2011;31(2):373-376. 
  20. Diordiev AV, Yakovleva ES, Adkina EA, Batysheva TT, Klimov YuA, Lazarev VV. Opioids are the best analgesics!... Or not? Prospects for opioidfree analgesia in children. Anesteziologiya i reanimatologiya. 2021;3:60-68. (In Russ.). https://doi.org/10.17116/anaesthesiology202103160
  21. Tola EN. The effect of anesthetic agents for oocyte pick-up on in vitro fertilization outcome: A retrospective study in a tertiary center. Taiwanese Journal of Obstetrics and Gynecology. 2019;58(5):673-679.  https://doi.org/10.1016/j.tjog.2019.07.016
  22. Hussein A, Hameedah M, Raad GR, Mufeeda AJ. Comparison between effects of ketamine and remifentanil used during oocyte retrieval on ICSI outcome. Systematic Reviews in Pharmacy. 2020;11(4):621-628. 
  23. Jarahzadeh MH, Jouya R, Mousavi FS, Dehghan-Tezerjani M, Behdad S, Soltani HR. Propofol or Thiopental sodium in patients undergoing reproductive assisted technologies: Differences in hemodynamic recovery and outcome of oocyte retrieval: A randomized clinical trial. Iranian Journal of Reproductive Medicine. 2014;12(1):77-82. 
  24. Oliveira GL Júnior, Serralheiro FC, Fonseca FL, Ribeiro OD Junior, Adami F, Christofolini DM, Bianco B, Barbosa CP. Randomized double-blind clinical trial comparing two anesthetic techniques for ultrasound-guided transvaginal follicular puncture. Einstein. 2016;14(3):305-310.  https://doi.org/10.1590/S1679-45082016AO3714
  25. Likhvantsev VV, Skripkin YuV, Grebenchikov OA, Shaposhnikov BA, Mironenko AV. Mechanisms of action and main effects of halogen-containing anesthetics. Vestnik intensivnoi terapii. 2013;3:44-51. (In Russ.).
  26. Likhvantsev VV, Yadgarov MYA, Di Piazza M, Kadantseva KK. Inhalation vs total intravenous anesthesia: where is the pendulum now? (meta-analysis and review). Obshchaya reanimatologiya. 2020;16(6):91-104. (In Russ.). https://doi.org/10.15360/1813-9779-2020-6-91-104
  27. Fujinada M, Baden JM, Shepard TH, Mazze RI. Nitrous oxide alters body laterality in rats. Teratology. 1990;41(2):131-135.  https://doi.org/10.1002/tera.1420410202
  28. Terui K. Evidence based anesthesiology for ART. Journal of Mammalian Ova Research. 2005;22(1):20-23.  https://doi.org/10.1274/jmor.22.20
  29. Orak Y, Tolun Fİ, Bakacak M, Yaylalı A, Kıran H, Öksüz H, Doğaner A, Yağmur I, Altun A. Effects of Propofol versus Sevoflurane on Postoperative Pain and Neuroendocrine Stress Response in Oocyte Pickup Patients. Pain Research and Management. 2021;2021:5517150. https://doi.org/10.1155/2021/5517150
  30. Potievskaya VI, Zabolotskikh IB, Gridchik IE, Gritsan AI, Eremenko AA, Kozlov IA, Lebedinskii KM, Levit AL, Mazurok VA, Molchanov IV, Nikolaenko EM. Sedation of patients in intensive care units. Anesteziologiya i reanimatologiya. 2020;(5):7-22. (In Russ.). https://doi.org/10.17116/anaesthesiology20200517
  31. Matsota P, Sidiropoulou T, Vrantza T, Boutsikou M, Midvighi E, Siristatidis C. Comparison of Two Different Sedation Protocols during Transvaginal Oocyte Retrieval: Effects on Propofol Consumption and IVF Outcome: A Prospective Cohort Study. Journal of Clinical Medicine. 2021;10(5):963.  https://doi.org/10.3390/jcm10050963
  32. Morue HI, Raj-Lawrence S, Saxena S, Delbaere A, Engelman E, Barvais LA. Placebo versus low-dose ketamine infusion in addition to remifentanil target-controlled infusion for conscious sedation during oocyte retrieval: A double-blinded, randomised controlled trial. European Journal of Anaesthesiology. 2018;35(9):667-674.  https://doi.org/10.1097/EJA.0000000000000826
  33. Matsota P, Sidiropoulou T, Vrantza T, Boutsikou M, Midvighi E, Siristatidis C. Comparison of Two Different Sedation Protocols during Transvaginal Oocyte Retrieval: Effects on Propofol Consumption and IVF Outcome: A Prospective Cohort Study. Journal of Clinical Medicine. 2021;10(5):963.  https://doi.org/10.3390/jcm10050963
  34. Elnabtity AM, Selim MF. A Prospective Randomized Trial Comparing Dexmedetomidine and Midazolam for Conscious Sedation during Oocyte Retrieval in an In Vitro Fertilization Program. Anesthesia, Essays and Researches. 2017;11(1):34-39.  https://doi.org/10.4103/0259-1162.167831
  35. Kwan I, Wang R, Pearce E, Bhattacharya S. Pain relief for women undergoing oocyte retrieval for assisted reproduction. Cochrane Database of Systematic Reviews. 2018;5(5):CD004829. https://doi.org/10.1002/14651858.CD004829.pub4
  36. Lier MC, Douwenga WM, Yilmaz F, Schats R, Hompes PG, Boer C, Mijatovic V. Patient-Controlled Remifentanil Analgesia as Alternative for Pethidine with Midazolam During Oocyte Retrieval in IVF/ICSI Procedures: A Randomized Controlled Trial. Pain Practice. 2015;15(5):487-495.  https://doi.org/10.1111/papr.12189
  37. Li Y, Mai Q, Li T, Zhong Y, Zhou C. The Clinic Analysis of Diclofenac Suppository for Oocyte Retrieval Analgesia in IVF-ET Cycles. International Journal of Clinical Medicine. 2013;4(8):350-354.  https://doi.org/10.4236/ijcm.2013.48062
  38. Zhao H, Feng Y, Jiang Y, Lu Q. Flurbiprofen axetil provides effective analgesia without changing the pregnancy rate in ultrasound-guided transvaginal oocyte retrieval: A double-blind randomized controlled trial. Anesthesia and Analgesia. 2017;125(4):1269-1274. https://doi.org/10.1213/ANE.0000000000002025
  39. Circeo L, Grow D, Kashikar A, Gibson C. Prospective, observational study of the depth of anesthesia during oocytes retrieval using a total intravenous anesthetic technique and Bispectral index monitor. Fertility and Sterility. 2011;96(3):635-637.  https://doi.org/10.1016/j.fertnstert.2011.06.010
  40. Heo HJ, Kim YY, Lee JH, Lee HG, Baek SM, Kim KM. Comparison of chemical pregnancy rates according to the anesthetic method during ultrasound-guided transvaginal oocyte retrieval for in vitro fertilization: a retrospective study. Anesthesia and Pain Medicine. 2020;15(1):49-52.  https://doi.org/10.17085/apm.2020.15.1.49
  41. Saxena D, Arya B, Dixit A, Sanwatsarkar S, Bhandari S, Agrawal P. Variations in anesthetic requirements with body mass index in patients undergoing trans vaginal oocyte retrieval. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2016;5:135-139.  https://doi.org/10.18203/2320-1770.ijrcog20151613
  42. Rolland L, Perrin J, Villes V, Pellegrin V, Boubli L, Courbiere B. IVF oocyte retrieval: prospective evaluation of the type of anesthesia on live birth rate, pain, and patient satisfaction. Journal of Assisted Reproduction and Genetics. 2017;34(11):1523-1528. https://doi.org/10.1007/s10815-017-1002-7
  43. Videnović N, Mladenvić J, Pavlović A, Trpković S, Filipović M, Markovic N, Stojković M. Analysis of the applied technique of intravenous anesthesia for in vitro fertilization in obese and patients with normal body mass index. Srpski Arhiv za Celokupno Lekarstvo. 2019;147(9-10):588-594.  https://doi.org/10.2298/SARH180227040V
  44. Qu F, Li R, Sun W, Lin G, Zhang R, Yang J, Tian L, Xing GG, Jiang H, Gong F, Liang XY, Meng Y, Liu JY, Zhou LY, Wang SY, Wu Y, He YJ, Ye JY, Han SP, Han JS. Use of electroacupuncture and transcutaneous electrical acupoint stimulation in reproductive medicine: a group consensus. Journal of Zhejiang University. Science. B. 2017;18(3):186-193.  https://doi.org/10.1631/jzus.B1600437
  45. Liang J, Ping XJ, Li YJ, Ma YY, Wu LZ, Han JS, Cui CL. Morphine-induced conditioned place preference in rats is inhibited by electroacupuncture at 2 Hz: role of enkephalin in the nucleus accumbens. Neuropharmacology. 2010;58(1):233-240.  https://doi.org/10.1016/j.neuropharm.2009.07.007
  46. Zhang Y, Zhang RX, Zhang M, Shen XY, Li A, Xin J, Ren K, Berman BM, Tan M, Lao L. Electroacupuncture inhibition of hyperalgesia in an inflammatory pain rat model: involvement of distinct spinal serotonin and norepinephrine receptor subtypes. British Journal of Anaesthesia. 2012;109(2):245-252.  https://doi.org/10.1093/bja/aes136
  47. Zhong J, Zhang L. [Transcutaneous electrical acupoint stimulation for pregnancy of in vitro fertilization-embryo transfer]. Zhongguo Zhen Jiu. 2017;37(3):253-255. Chinese. https://doi.org/10.13703/j.0255-2930.2017.03.008
  48. Qu F, Wang FF, Wu Y, Zhou J, Robinson N, Hardiman PJ, Pan JX, He YJ, Zhu YH, Wang HZ, Ye XQ, He KL, Cui L, Zhao HL, Ye YH. Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of In Vitro Fertilization: A Prospective, Randomized and Controlled Study. Explore. 2017;13(5):306-312.  https://doi.org/10.1016/j.explore.2017.06.004
  49. Chen QQ, Wei QL, Zhang XH. [Effects of electroacupuncture on supplementary analgesia and improvement of adverse reactions induced by dolantin in oocyte retrieval]. Zhongguo Zhen Jiu. 2012;32(12):1113-1116.
  50. Wong QHY, Lui MW, Yung SSF, Ko JKY, Li RHW, Ng EHY. Randomized controlled trial of transcutaneous electrical nerve stimulation for pain relief during transvaginal oocyte retrieval using conscious sedation: study protocol for a randomized controlled trial. Trials. 2019;20(1):205.  https://doi.org/10.1186/s13063-019-3227-5
  51. Piroli A, Marci R, Marinangeli F, Paladinin A, Di Emidio G, Artini PG, Caserta D, Tatone C. Comparison of different anesthetic methodologies for sedation during in vitro fertilization procedures: effects on patients physiology and oocyte competence. Gynecological Endocrinology. 2012;28(10):796-799.  https://doi.org/10.3109/09513590.2012.664193
  52. Catoire P, Delaunay L, Dannappel T, Baracchini D, Marcadet-Fredet S, Moreau O, Pacaud L, Przyrowski D, Marret E. Hypnosis versus diazepam for embryo transfer: a randomized controlled study. The American Journal of Clinical Hypnosis. 2013;55(4):378-386.  https://doi.org/10.1080/00029157.2012.747949

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.