Urgent plasma exchange in the treatment of thrombotic microangiopathy in postpartum period in women

Kirsanova T.V.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Fedorova T.A.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Gurbanova S.R.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Balakireva A.I.

Lomonosov Moscow State University

Rogachevsky O.V.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Vinogradova M.A.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Zav’yalova I.V.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

ORCID: 0000-0002-0893-476X

Urgent plasma exchange in the treatment of thrombotic microangiopathy in postpartum period in women

Authors:

Kirsanova T.V., Fedorova T.A., Gurbanova S.R., Balakireva A.I., Rogachevsky O.V., Vinogradova M.A., Zav’yalova I.V.

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Journal: Russian Journal of Anesthesiology and Reanimatology. 2020;(5): 85‑91

DOI: 10.17116/anaesthesiology202005185

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To cite this article:

Kirsanova TV, Fedorova TA, Gurbanova SR, Balakireva AI, Rogachevsky OV, Vinogradova MA, Zav’yalova IV. Urgent plasma exchange in the treatment of thrombotic microangiopathy in postpartum period in women. Russian Journal of Anesthesiology and Reanimatology. 2020;(5):85‑91. (In Russ.)
https://doi.org/10.17116/anaesthesiology202005185

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Pregnancy complications, such as various thrombotic microangiopathies (TMA), are characterized by fast development of severe symptoms followed by multiple organ failure. This process is life-threatening for mother and fetus. In this regard, timely therapy is the most urgent issue. Treatment strategy is complicated by difficult differential diagnosis of the TMA type. We report atypical hemolytic-uremic syndrome associated with pregnancy, discuss the recommended treatment regimens and importance of timely plasma exchange to achieve favorable outcome. Urgent plasma exchange is a first-line method for any type of thrombotic microangiopathy.

Keywords:

plasma exchange

thrombotic microangiopathy

pregnancy

atypical hemolytic uremic syndrome

Authors:

Kirsanova T.V.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Fedorova T.A.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Gurbanova S.R.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Balakireva A.I.

Lomonosov Moscow State University

Rogachevsky O.V.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Vinogradova M.A.

Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Zav’yalova I.V.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

ORCID: 0000-0002-0893-476X

Received:

28.04.2020

Accepted:

14.05.2020

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