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Yaroustovsky M.B.
Bakulev National Medical Research Center for Cardiovascular Surgery
Shukevich D.L.
Research Institute for Complex Issues of Cardiovascular Diseases
Ushakova N.D.
National Oncology Research Center
Sokolov A.A.
Mechnikov North-Western State Medical University
Rey S.I.
Sklifosovsky Research Institute of Emergency Care
Blood purification methods in complex treatment of patients with a new coronavirus infection
Journal: Russian Journal of Anesthesiology and Reanimatology. 2020;(5): 47‑55
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To cite this article:
Yaroustovsky MB, Shukevich DL, Ushakova ND, Sokolov AA, Rey SI. Blood purification methods in complex treatment of patients with a new coronavirus infection. Russian Journal of Anesthesiology and Reanimatology.
2020;(5):47‑55. (In Russ.)
https://doi.org/10.17116/anaesthesiology202005147
Blood purification methods are widely used for sepsis, systemic inflammatory response and multiple organ failure. The new coronavirus infection followed by sepsis or septic shock in severe cases is characterized by imbalance in concentrations of pro- and anti-inflammatory mediators (the so-called cytokine storm). These processes result the development and progression of multiple organ failure. Special attention is paid to impaired renal function, since acute renal damage in COVID-19 is a predictor of an adverse outcome. In this situation, blood purification methods are advisable for discontinuation of cytokine storm on the one hand and treatment/prevention of acute kidney injury on the other one. The authors describe blood purification methods which are currently used in the treatment of sepsis and septic shock and can be used for COVID-19. Effectiveness of some of these techniques have been already confirmed. The issues of acute renal injury and options for renal replacement therapy are also considered.
Keywords:
Authors:
Yaroustovsky M.B.
Bakulev National Medical Research Center for Cardiovascular Surgery
Shukevich D.L.
Research Institute for Complex Issues of Cardiovascular Diseases
Ushakova N.D.
National Oncology Research Center
Sokolov A.A.
Mechnikov North-Western State Medical University
Rey S.I.
Sklifosovsky Research Institute of Emergency Care
Received:
05.04.2020
Accepted:
12.07.2020
List of references:
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