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Churyukanov M.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
B.V. Petrovsky Russian Scientific Center of Surgery

Amelin A.V.

I.P. Pavlov First Saint Petersburg State Medical University

Akhmadeeva L.R.

Bashkir State Medical University

Davydov O.S.

Research Institute of General Pathology and Pathophysiology

Kukushkin M.L.

Research Institute of General Pathology and Pathophysiology

Shirokov V.A.

F.F. Erisman Federal Scientific Center of Hygiene

Resolution of the extended meeting of the Presidium and committees of the Russian Association for the Study of Pain (RASP) “The role of central muscle relaxants in the treatment of non-specific low back pain”

Authors:

Churyukanov M.V., Amelin A.V., Akhmadeeva L.R., Davydov O.S., Kukushkin M.L., Shirokov V.A.

More about the authors

Journal: Russian Journal of Pain. 2025;23(2): 91‑91

DOI: 10.17116/pain20252302191

Read: 604 times

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Table of contents

RESOLUTION OF THE EXTENDED MEETING OF THE PRESIDIUM AND COMMITTEES OF THE RUSSIAN ASSOCIATION FOR THE STUDY OF PAIN (RASP) “THE ROLE OF CENTRAL MUSCLE RELAXANTS IN THE TREATMENT OF NON-SPECIFIC LOW BACK PAIN”
RESOLUTION OF THE EXTENDED MEETING OF THE PRESIDIUM AND COMMITTEES OF THE RUSSIAN ASSOCIATION FOR THE STUDY OF PAIN (RASP) “THE ROLE OF CENTRAL MUSCLE RELAXANTS IN THE TREATMENT OF NON-SPECIFIC LOW BACK PAIN”

To cite this article:

Churyukanov MV, Amelin AV, Akhmadeeva LR, Davydov OS, Kukushkin ML, Shirokov VA. Resolution of the extended meeting of the Presidium and committees of the Russian Association for the Study of Pain (RASP) “The role of central muscle relaxants in the treatment of non-specific low back pain”. Russian Journal of Pain. 2025;23(2):91‑91. (In Russ.)
https://doi.org/10.17116/pain20252302191

Подписка 2025 Российский журнал боли (Russian Journal of Pain)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

In December 2024, an extended meeting of the Presidium and committees of the Russian Association for the Study of Pain (RASP) was held, during which the role of central muscle relaxants in the treatment of non-specific low back pain was discussed. The meeting presented data from studies of the efficacy and safety of orphenadrine as part of an infusion fixed combination with diclofenac, tizanidine as monotherapy and as part of fixed combination with mirtazapine, tolperisone, chlorzoxazone as part of fixed combination with ibuprofen, cyclobenzaprine and eperisone in the treatment of musculoskeletal back pain.

Keywords:

central muscle relaxants
musculoskeletal back pain
pain treatment
clinical guidelines

Authors:

Churyukanov M.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
B.V. Petrovsky Russian Scientific Center of Surgery

Amelin A.V.

I.P. Pavlov First Saint Petersburg State Medical University

Akhmadeeva L.R.

Bashkir State Medical University

Davydov O.S.

Research Institute of General Pathology and Pathophysiology

Kukushkin M.L.

Research Institute of General Pathology and Pathophysiology

Shirokov V.A.

F.F. Erisman Federal Scientific Center of Hygiene

Received:

07.04.2025

Accepted:

11.04.2025

Close metadata

References:

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  2. GBD 2021 Low Back Pain Collaborators. Global, regional, and national burden of low back pain, 1990-2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023 May 22;5(6):e316-e329. https://doi.org/10.1016/S2665-9913(23)00098-X.
  3. van Tulder MW, Touray T, Furlan AD, Solway S, Bouter LM. Muscle relaxants for non-specific low back pain (Review). Cochrane Database of Systematic Reviews. 2003;4:CD004252. https://doi.org/10.1002/14651858.CD004252
  4. Shaheed AC, Maher CG, Williams KA, McLachlan AJ. Efficacy and tolerability of muscle relaxants for low back pain: Systematic review and metaanalysis. Eur J Pain. 2017;21(2):228-237.  https://doi:10.1002/ejp.90713.
  5. Chang WJ. Muscle Relaxants for Acute and Chronic Pain. Phys Med Rehabil Clin N Am. 2020 May;31(2):245-254.  https://doi.org/10.1016/j.pmr.2020.01.005.
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  7. https://doi.org/10.17116/pain20222001133 
  8. Dolin SJ, Cashman JN, Bland JM. Effectiveness of acute postoperative pain management: I. Evidence from published data. British Journal of Anaesthesia. 2002;89:409-423.  https://doi.org/10.18821/1993-6508-2016-10-1-40-46
  9. Karim Z, Schug SA. Function in Response to Acute Pain In: Encyclopedia of Pain. Schmidt RF, Willis WD, eds. Springer Berlin Heidelberg; 2006.
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  11. https://doi.org/10.17116/pain20242203159 
  12. https://doi.org/10.17116/pain20252301192 
  13. Skoromets AA, Gekht AB, Galanov DV, et al. The results of the multicenter pharmaco-epidemiological observational project on the use of mydocalm in the treatment of pain syndromes with the muscle spasm. S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(12):104-109. (In Russ.). https://doi.org/10.17116/jnevro2015115112104-109
  14. Kukushkin ML, Brylev LV, Laskov VB, et al. Results of a randomized double blind parallel study on the efficacy and safety of tolpersione in patients with acute nonspecific low back pain. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(11):69-78. (In Russ.). https://doi.org/10.17116/jnevro201711711169-78
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  18. Kalofonos I, Stahly GP, et al., 2011. Novel form of eperisone. Patent Application Publication doi: US 2011/0281911A1. https://patentimages.storage.googleapis.com/6c/7a/4a/31483b7d6a8e2b/US20110281911A1.pdf
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