Pleura damage in COVID-19, experience of treatment during eighteen months of the pandemic

Close metadata

BACKGROUND

Pleural lessons and developing intrapleural complications are a complication of pneumonia caused by SARS-CoV-2.

MATERIAL AND METHODS

A multicenter retrospective study was conducted, including 1356 patients with pneumonia caused by COVID-19.

RESULTS

The prevalence of pathological changes in the pleura (thickening and retraction) was 33.6% (in 455 patients). The incidence of pleural effusion with SARS-CoV-2 lung parenchyma damage was 7.3% (in 99 patients). Pneumothorax developed in 17 (1.25%) patients.

CONCLUSION

Involvement of the pleura in COVID-19 is associated with a worsening of the condition and a deterioration in the overall prognosis of the lesion.

Keywords:

pleural lesion in COVID-19

spontaneous pneumothorax

pleural effusion in SARS-CoV-2

Authors:

D.Sh. Salimov

Mandryk Central Military Clinic Hospital

ORCID: 0000-0001-8647-1505

A.A. Vorobev

Moscow Research Clinical Center for Tuberculosis Control

SPIN RSCI: 6760-9424

Received:

04.02.2022

Accepted:

17.03.2022

List of references:

Saha BK, Bonnier A, Chong W. Antimalarials as Antivirals for COVID-19: Believe it or Not! Am J Med Sci. 2020;360:618-630. https://doi.org/10.1016/j.amjms.2020.08.019
Ackermann M, Verleden SE, Kuehnel M. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N Engl J Med. 2020;383:120-128. https://doi.org/10.1056/NEJMoa2015432
Xu X, Yu C, Qu J. Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2. Eur J Nucl Med Mol Imaging. 2020;47:1275-1280. https://doi.org/10.1007/s00259-020-04735-9
Zhou S, Wang Y, Zhu T. CT Features of Coronavirus Disease 2019 (COVID-19) Pneumonia in 62 Patients in Wuhan, China. AJR Am J Roentgenol. 2020;214:1287-1294. https://doi.org/10.2214/AJR.20.22975
Salehi S, Abedi A, Balakrishnan S. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients. AJR Am J Roentgenol. 2020;215:87-93. https://doi.org/10.2214/AJR.20.23034
Langenbach MC, Hokamp NG, Persigehl T. MRI appearance of COVID-19 infection. Diagn Interv Radiol. 2020;26:377-378. https://doi.org/10.5152/dir.2020.20152
Falguera M, Carratalà J, Bielsa S. Predictive factors, microbiology and outcome of patients with parapneumonic effusion. Eur Respir J. 2011;38:1173-1179. https://doi.org/10.1183/09031936.00000211
Sahn SA. Diagnosis and management of parapneumonic effusions and empyema. Clin Infect Dis. 2007;45:1480-1486. https://doi.org/10.1086/522996
Schaller T, Hirschbühl K, Burkhardt K, et al. Postmortem Examination of Patients With COVID-19. JAMA. 2020;323:2518-2520. https://doi.org/10.1001/jama.2020.8907
Sahn SA. The pathophysiology of pleural effusions. Annu Rev Med. 1990;41:7-13. https://doi.org/10.1146/annurev.me.41.020190.000255
Ducloyer M, Gaborit B, Toquet C. Complete post-mortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations. Int J Legal Med. 2020;134:209-214. https://doi.org/10.1007/s00414-020-02390-1
Xiang C, Lu J, Zhou J. CT Findings in a Novel Coronavirus Disease (COVID-19) Pneumonia at Initial Presentation. Biomed Res Int. 2020;20(2):543-550. https://doi.org/10.1155/2020/5436025
Adams HJA, Kwee TC, Yakar D. Chest CT Imaging Signature of Coronavirus Disease 2019 Infection: In Pursuit of the Scientific Evidence. Chest. 2020;158:1885-1895. https://doi.org/10.1016/j.chest.2020.06.025
Fu Z, Tang N, Chen Y. CT features of COVID-19 patients with two consecutive negative RT-PCR tests after treatment. Sci Rep. 2020;10:11548. https://doi.org/10.1038/s41598-020-68509-x
López Vega JM, Parra Gordo ML, Diez Tascón A. Pneumomediastinum and spontaneous pneumothorax as an extrapulmonary complication of COVID-19 disease. Emerg Radiol. 2020;27(6):727-730. https://doi.org/10.1007/s10140-020-01806-0
British Thoracic Society. Pleural Services During the COVID-19 Pandemic — Revised. Available from: May 21, 2020.
Zantah M, Dominguez Castillo E, Townsend R. Pneumothorax in COVID-19 disease- incidence and clinical characteristics. Respir Res. 2020;21:236-237. https://doi.org/10.1186/s12931-020-01504-y
Gattinoni L, Coppola S, Cressoni M. COVID-19 Does Not Lead to a «Typical» Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020;20(1):1299-1300. https://doi.org/10.1164/rccm.202003-0817LE
Mallick T, Dinesh A, Engdahl R. COVID-19 Complicated by Spontaneous Pneumothorax. Cureus. 2020;12(7):91-94. https://doi.org/10.7759/cureus.9104
Shah V, Brill K, Dhingra G. Delayed recurrent spontaneous pneumothorax in a patient recovering from COVID-19 pneumonia. Korean J Anesthesiol. 2021;7(4):183-185. https://doi.org/10.4097/kja.20400
Hsu NY, Shih CS, Hsu CP, Chen PR. Spontaneous hemopneumothorax revisited: clinical approach and systemic review of the literature. Ann Thorac Surg. 2005;80(5):1859-1863. https://doi.org/10.1016/j.athoracsur.2005.04.052
Al-Samkari H, Karp Leaf RS, Dzik WH. COVID and coagulation: bleeding and thrombotic manifestations of SARS-CoV2 infection. Blood. 2020;136(4):489-500. https://doi.org/10.1182/blood.2020006520
Haciibrahimoglu G, Cansever L, Kocaturk CI, Aydogmus U, Bedirhan MA. Spontaneous hemopneumothorax: is conservative treatment enough? Thorac Cardiovasc Surg. 2005;53(4):240-242. https://doi.org/10.1055/s-2005-837647
de Perrot M, Deléaval J, Robert J, Spiliopoulos A. Spontaneous hemopneumothorax — results of conservative treatment. Swiss Surg. 2000;6(2):62-64. https://doi.org/10.1024/1023-9332.6.2.62
Nayak R, Brogly SB, Lajkosz K, Lougheed MD, Petsikas D. Outcomes of operative and nonoperative treatment of thoracic empyema: a population-based Study. Ann Thorac Surg. 2019;108(7):1456-1463. https://doi.org/10.1016/j.athoracsur.2019.05.090