Features of decision-making in patients with alcohol dependence

Galkin S.A.; Oshkina T.A.; Kisel N.I.

doi:https://doi.org/10.17116/jnevro2023123081115

Galkin S.A.

Mental Health Research Institute of the Tomsk National Research Medical Center of the Russian Academy of Science

ORCID: 0000-0002-7709-3917

Oshkina T.A.

Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0003-0927-0050

Kisel N.I.

Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0001-5573-9775

Features of decision-making in patients with alcohol dependence

Authors:

Galkin S.A., Oshkina T.A., Kisel N.I.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(8): 115‑119

DOI: 10.17116/jnevro2023123081115

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To cite this article:

Galkin SA, Oshkina TA, Kisel NI. Features of decision-making in patients with alcohol dependence. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(8):115‑119. (In Russ.)
https://doi.org/10.17116/jnevro2023123081115

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

Использование инфографики авторами научных работ

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OBJECTIVE

To identify electroencephalographic correlates of decision—making features in patients with alcohol dependence.

MATERIAL AND METHODS

Forty men with alcohol dependence were examined as the main group. Thirty people were examined as a control group. The Cambridge Gambling Task and the Iowa Gambling Task were used to study decision—making functions. Additionally, a background electroencephalogram was recorded with the calculation of absolute spectral power indicators

RESULTS

In the main group, the relatively higher indicators of decision—making logic (65 [50; 80]%, p<0.05) were associated with larger values of the spectral power of the theta and alpha rhythm of the electroencephalogram in the central and parietal-occipital leads (R=0.426, p=0.019; R=0.418, p=0.022; R=0.394, p=0.028 and R=0.445, p=0.014; R=0.458, p=0.011; R=0.382, p=0.035, respectively). Difficulties in making decisions based on emotional learning in patients with alcohol dependence were associated with larger values of the spectral power of the beta rhythm of the electroencephalogram in the temporal leads.

CONCLUSIONS

The study showed that the deficit of decision—making functions in patients with alcohol dependence may be due to an imbalance of the excitation/inhibition mechanisms in the brain.

Keywords:

alcohol use disorders

decision—making

logic

emotional learning

electroencephalography

Authors:

Galkin S.A.

Mental Health Research Institute of the Tomsk National Research Medical Center of the Russian Academy of Science

ORCID: 0000-0002-7709-3917

Oshkina T.A.

Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0003-0927-0050

Kisel N.I.

Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0001-5573-9775

Received:

18.03.2023

Accepted:

01.05.2023

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