Arterial hypertension and cognitive impairment. Neurologist’s view

Fedin A.I.

doi:https://doi.org/10.17116/jnevro20231231117

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Abstract:

The article presents a review of the literature on the relationship of cognitive impairment (CI) with arterial hypertension (AH). The pathogenetic mechanisms AH are characterized by the development of cerebral microangiopathy. Antihypertensive therapy (AHT) should take into account violations of autoregulation of cerebral blood flow in cerebrovascular disease and critical stenoses of large cerebral arteries, especially in fragile patients older than 80 years. The importance of AHT focused on the level of cerebral perfusion blood pressure, the severity of CI and the physical functioning of patients is emphasized. Neurocytoprotective therapy is recommended for correction of CI.

Keywords:

arterial hypertension

cognitive impairment

antihypertensive therapy

cerebral perfusion blood pressure

Authors:

Fedin A.I.

Pirogov Russian National Research Medical University

SPIN RSCI: 8834-0085
Scopus AuthorID: 7007163263
ORCID: 0000-0002-6996-2828

Received:

28.07.2023

Accepted:

07.09.2023

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References:

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