The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Ivanets N.N.

Sechenov First Moscow State Medical University (Sechenov University)

Kinkulkina M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Tikhonova Yu.G.

Sechenov First Moscow State Medical University (Sechenov University)

Makarova M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Sysoeva V.P.

Sechenov First Moscow State Medical University (Sechenov University)

Unipolar depression: a gender-based comparative analysis

Authors:

Ivanets N.N., Kinkulkina M.A., Tikhonova Yu.G., Makarova M.A., Sysoeva V.P.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(8): 13‑18

DOI: 10.17116/jnevro202112108113

Read: 3719 times

Download PDF (RU)
Contact the author
Table of contents

UNIPOLAR DEPRESSION: A GENDER-BASED COMPARATIVE ANALYSIS
UNIPOLAR DEPRESSION: A GENDER-BASED COMPARATIVE ANALYSIS

To cite this article:

Ivanets NN, Kinkulkina MA, Tikhonova YuG, Makarova MA, Sysoeva VP. Unipolar depression: a gender-based comparative analysis. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(8):13‑18. (In Russ.)
https://doi.org/10.17116/jnevro202112108113

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
The state of mental health of migrant workers and citi­zens of the Russian Fede­ration: A comparative analysis as illu­strated by the Moscow region. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(4):95-101
Factors of depression acco­rding to acti­graphy in the fall season. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5-2):27-32
Identification of depression biomarkers: Prospects for use in clinical practice. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5):51-55
Depression Anxiety Stress Scale (russian language version). S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5):103-107
Inve­stigation of the rela­tionship of indi­vidual characteristics of the brain bioelectrical acti­vity with levels of mental stress, aggression, anxiety, and depression. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5):108-117
Modern concepts of sleep disturbances asso­ciated with mental diso­rders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(6):7-12
Vali­dation of the Snaith—Hamilton Pleasure Scale to assess anhe­donia in patients with unipolar depression In Russia. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7):110-121
Gender differences in vertebrobasilar hemo­dynamics in response to manual-physical impact in the treatment of esse­ntial arte­rial hype­rtension using the method of A.Yu. Shishonin. Problems of Balneology, Physiotherapy and Exercise Therapy. 2025;(2):5-10
Gender characteristics of cardiovascular diseases psychosocial risk factors asso­ciations with sleep quality in an open urban popu­lation. Russian Journal of Preventive Medi­cine. 2025;(6):67-73
Dysfunctional pelvic pain in women. Russian Journal of Pain. 2025;(2):32-37
Abstract:

OBJECTIVE

To compare socio-demographic and clinical characteristics in men and women with depression.

MATERIAL AND METHODS

We studied 388 patients with unipolar depression, 74 men and 314 women. The survey was carried out using the clinical-psychopathological method and psychometric scales for depression.

RESULTS AND CONCLUSION

Gender differences are identified for several parameters. Women are older, more often had comorbid somatic and organic disorders; men have personality disorders and chronic depression. The severity of depression in women was higher due to symptoms such as reported sadness, anxiety, reduced sleep and appetite, concentration difficulties, and suicidal thoughts. Apparent sadness did not significantly differ in men and women. Anhedonia was more pronounced in men.

Keywords:

depression
gender differences
symptom profiles
comparative study

Authors:

Ivanets N.N.

Sechenov First Moscow State Medical University (Sechenov University)

Kinkulkina M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Tikhonova Yu.G.

Sechenov First Moscow State Medical University (Sechenov University)

Makarova M.A.

Sechenov First Moscow State Medical University (Sechenov University)

Sysoeva V.P.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

10.02.2021

Accepted:

16.02.2021

Close metadata

References:

  1. Riecher-Rössler A. Prospects for the classification of mental disorders in women. Eur Psychiatry. 2010;25(4):189-196.  https://doi.org/10.1016/j.eurpsy.2009.03.002
  2. Karger A. Geschlechtsspezifische Aspekte bei depressiven Erkrankungen [Gender differences in depression]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014;57(9):1092-1098. https://doi.org/10.1007/s00103-014-2019-z
  3. Boyd A, Van de Velde S, Vilagut G, de Graaf R, O’Neill S, Florescu S, Alonso J, Kovess-Masfety V; EU-WMH Investigators. Gender differences in mental disorders and suicidality in Europe: results from a large cross-sectional population-based study. J Affect Disord. 2015;173:245-254.  https://doi.org/10.1016/j.jad.2014.11.002
  4. Seedat S, Scott KM, Angermeyer MC, Berglund P, Bromet EJ, Brugha TS, Demyttenaere K, de Girolamo G, Haro JM, Jin R, Karam EG, Kovess-Masfety V, Levinson D, Medina Mora ME, Ono Y, Ormel J, Pennell BE, Posada-Villa J, Sampson NA, Williams D, Kessler RC. Cross-national associations between gender and mental disorders in the World Health Organization World Mental Health Surveys. Arch Gen Psychiatry. 2009;66(7):785-795.  https://doi.org/10.1001/archgenpsychiatry.2009.36
  5. Wittchen HU, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jönsson B, Olesen J, Allgulander C, Alonso J, Faravelli C, Fratiglioni L, Jennum P, Lieb R, Maercker A, van Os J, Preisig M, Salvador-Carulla L, Simon R, Steinhausen HC. The size and burden of mental disorders and other disorders of the brain in Europe 2010. European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology. 2011;21(9):655-679.  https://doi.org/10.1016/j.euroneuro.2011.07.018
  6. Riecher-Rössler A. Oestrogens, prolactin, hypothalamic-pituitary-gonadal axis, and schizophrenic psychoses. Lancet Psychiatry. 2017;4(1):63-72.  https://doi.org/10.1016/S2215-0366(16)30379-0
  7. Abate KH. Gender disparity in prevalence of depression among patient population: a systematic review. Ethiop J Health Sci. 2013;23(3):283-288.  https://doi.org/10.4314/ejhs.v23i3.11
  8. Donner NC, Lowry CA. Sex differences in anxiety and emotional behavior. Pflugers Arch. 2013;465(5):601-626.  https://doi.org/10.1007/s00424-013-1271-7
  9. Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG, Joyce PR, Karam EG, Lee CK, Lellouch J, Lépine JP, Newman SC, Rubio-Stipec M, Wells JE, Wickramaratne PJ, Wittchen H, Yeh EK. Cross-national epidemiology of major depression and bipolar disorder. JAMA. 1996;276(4):293-299. 
  10. Kessler RC, McGonagle KA, Swartz M, Blazer DG, Nelson CB. Sex and depression in the National Comorbidity Survey. I: Lifetime prevalence, chronicity and recurrence. J Affect Disord. 1993;29(2-3):85-96.  https://doi.org/10.1016/0165-0327(93)90026-g
  11. Cyranowski JM, Frank E, Young E, Shear MK. Adolescent onset of the gender difference in lifetime rates of major depression: a theoretical model. Arch Gen Psychiatry. 2000;57(1):21-27.  https://doi.org/10.1001/archpsyc.57.1.21
  12. Keitner GI, Ryan CE, Miller IW, Kohn R, Epstein NB. 12-month outcome of patients with major depression and comorbid psychiatric or medical illness (compound depression). Am J Psychiatry. 1991;148(3):345-350.  https://doi.org/10.1176/ajp.148.3.345
  13. Ernst C, Angst J. The Zurich Study. XII. Sex differences in depression. Evidence from longitudinal epidemiological data. Eur Arch Psychiatry Clin Neurosci. 1992;241(4):222-230.  https://doi.org/10.1007/BF02190257
  14. Winokur G, Coryell W, Keller M, Endicott J, Akiskal H. A prospective follow-up of patients with bipolar and primary unipolar affective disorder. Arch Gen Psychiatry. 1993;50(6):457-465.  https://doi.org/10.1001/archpsyc.1993.01820180059006
  15. Kornstein SG, Schatzberg AF, Yonkers KA, Thase ME, Keitner GI, Ryan CE, Schlager D. Gender differences in presentation of chronic major depression. Psychopharmacol Bull. 1995;31(4):711-718. 
  16. Reisner SL, Katz-Wise SL, Gordon AR, Corliss HL, Austin SB. Social Epidemiology of Depression and Anxiety by Gender Identity. J Adolesc Health. 2016;59(2):203-208.  https://doi.org/10.1016/j.jadohealth.2016.04.006
  17. Riecher-Rössler A. Sex and gender differences in mental disorders. Lancet Psychiatry. 2017;4(1):8-9.  https://doi.org/10.1016/S2215-0366(16)30348-0
  18. Kinrys G, Wygant LE. Transtornos de ansiedade em mulheres: gênero influencia o tratamento? [Anxiety disorders in women: does gender matter to treatment?]. Braz J Psychiatry. 2005;27(suppl 2):43-50.  https://doi.org/10.1590/s1516-44462005000600003
  19. Grigoriadis S, Robinson GE. Gender issues in depression. Ann Clin Psychiatry. 2007;19(4):247-255.  https://doi.org/10.1080/10401230701653294
  20. Dekker J, Koelen JA, Peen J, Schoevers RA, Gijsbers-van Wijk C. Gender differences in clinical features of depressed outpatients: preliminary evidence for subtyping of depression? Women Health. 2007;46(4):19-38.  https://doi.org/10.1300/j013v46n04_02
  21. Silverstein B. Gender difference in the prevalence of clinical depression: the role played by depression associated with somatic symptoms. Am J Psychiatry. 1999;156(3):480-482. 
  22. Exploring the Biological Contributions to Human Health. Does Sex Matter? Institute of Medicine (US) Committee on Understanding the Biology of Sex and Gender Differences; Editors: Theresa M. Wizemann and Mary-Lou Pardue. Washington (DC): National Academies Press (US); 2001.
  23. Zucker KJ. Reports from the DSM-V Work Group on sexual and gender identity disorders. Arch Sex Behav. 2010;39(2):217-220.  https://doi.org/10.1007/s10508-009-9548-9
  24. Nazroo JY, Edwards AC, Brown GW. Gender differences in the onset of depression following a shared life event: a study of couples. Psychol Med. 1997;27(1):9-19.  https://doi.org/10.1017/s0033291796004187
  25. Kendler KS, Gardner CO. Sex differences in the pathways to major depression: a study of opposite-sex twin pairs. Am J Psychiatry. 2014;171(4):426-435.  https://doi.org/10.1176/appi.ajp.2013.13101375
  26. van Loo HM, Aggen SH, Gardner CO, Kendler KS. Multiple risk factors predict recurrence of major depressive disorder in women. J Affect Disord. 2015;180:52-61.  https://doi.org/10.1016/j.jad.2015.03.045
  27. Li SH, Graham BM. Why are women so vulnerable to anxiety, trauma-related and stress-related disorders? The potential role of sex hormones. Lancet Psychiatry. 2017;4(1):73-82.  https://doi.org/10.1016/S2215-0366(16)30358-3
  28. Kuehner C. Why is depression more common among women than among men? Lancet Psychiatry. 2017;4(2):146-158.  https://doi.org/10.1016/S2215-0366(16)30263-2
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.