Pain syndromes and insomnia: the role of association with comorbid mental disorders (on the model of glossalgia)

Yuzbashyan P.G.; Lvov A.N.; Tereshchenko A.V.; Volel’ B.A.; Satrudinova R.R.; Romanov D.V.

doi:https://doi.org/10.17116/jnevro202112110113

Yuzbashyan P.G.

Sechenov First Moscow State Medical University (Sechenov University)

ORCID: 0000-0002-7441-5546

Lvov A.N.

Central State Medical Academy Department for Presidential Affairs of the Russian Federation;
Medical Research and Education Center of Lomonosov Moscow State University

ORCID: 0000-0003-2737-3432

Tereshchenko A.V.

Kaluga branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Volel’ B.A.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

ORCID: 0000-0003-1667-5355

Satrudinova R.R.

Sechenov First Moscow State Medical University (Sechenov University)

Romanov D.V.

Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

ORCID: 0000-0002-1822-8973

Pain syndromes and insomnia: the role of association with comorbid mental disorders (on the model of glossalgia)

Authors:

Yuzbashyan P.G., Lvov A.N., Tereshchenko A.V., Volel’ B.A., Satrudinova R.R., Romanov D.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(10): 13‑18

DOI: 10.17116/jnevro202112110113

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To cite this article:

Yuzbashyan PG, Lvov AN, Tereshchenko AV, Volel’ BA, Satrudinova RR, Romanov DV. Pain syndromes and insomnia: the role of association with comorbid mental disorders (on the model of glossalgia). S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(10):13‑18. (In Russ.)
https://doi.org/10.17116/jnevro202112110113

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

To test the association between pain severity and anxiety, depression, and somatoform symptoms in burning sleep syndrome (BMS).

MATERIAL AND METHODS

The study included 36 patients (33 women, 3 men), mean age 58.0±14.8 years. Psychopathological, clinical-dermatological, parametric, statistical methods were used. Psychometric examination included the Visual Analogue Scale (VAS) for assessment of pain (severity of glossalgia), PHQ-4 for self-assessment of severity of anxiety (GAD-2) and depression (PHQ-2), the Hospital Anxiety and Depression Scale (HADS), the Screening for Somatoform Symptoms-2 (SOMS-2), the Pittsburgh Sleep Quality Index (PSQI), the EQ-5D-5L quality of life assessment scale.

RESULTS AND CONCLUSION

Insomnia in chronic pain is very common. On the one hand, studies show that sleep deprivation can enhance pain perception. On the other hand, chronic pain can trigger a variety of sleep disorders. One of the localizations of chronic pain syndrome is the oral mucosa. Somatoform pain disorder related to oral mucosa called «glossalgia» or «burning mouth syndrome» (BMS). The prevalence of insomnia in the study sample was 61.1%. The statistically significant positive correlation was found between the severity of insomnia (PSQI) and the severity of anxiety on both GAD-2 and HADS, while insomnia showed no correlation with depression and pain severity. At the same time, the severity of anxiety showed statistically significant positive correlation with the severity of pain assessed by VAS.

Keywords:

burning sleep syndrome

glossalgia

pain

insomnia

anxiety

depression

somatoform disorders

Authors:

Yuzbashyan P.G.

Sechenov First Moscow State Medical University (Sechenov University)

ORCID: 0000-0002-7441-5546

Lvov A.N.

Central State Medical Academy Department for Presidential Affairs of the Russian Federation;
Medical Research and Education Center of Lomonosov Moscow State University

ORCID: 0000-0003-2737-3432

Tereshchenko A.V.

Kaluga branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Volel’ B.A.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

ORCID: 0000-0003-1667-5355

Satrudinova R.R.

Sechenov First Moscow State Medical University (Sechenov University)

Romanov D.V.

Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

ORCID: 0000-0002-1822-8973

Received:

02.03.2021

Accepted:

18.03.2021

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