Pain perception and nonsuicidal self-injurious behavior

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This review focuses on studies of pain threshold and tolerance in individuals with nonsuicidal self-injurious (NSSI) behavior. The data on methods of pain sensitivity studies are presented, with issues in animal modeling of NSSI discussed separately. The results of neuroimaging studies on pain sensitivity in individuals with NSSI are described, along with contribution of genetic factors, psychological variables, and disturbances in opioid and hypothalamic-pituitary-adrenal systems. A critical methodological analysis of the studies on pain sensitivity in individuals with NSSI was performed.

Keywords:

nonsuicidal self-injurious behavior

pain

borderline personality disorder

mental disorders

Authors:

Zinchuk M.S.

Moscow Research and Clinical Centre for Neuropsychiatry

ORCID: 0000-0002-2538-3314

Avedisova A.S.

Serbsky National Medical Research Centre for Psychiatry and Narcology, the Ministry of Health of the Russian Federation

SPIN RSCI: 4339-6749
Scopus AuthorID: 6602410560

Voinova N.I.

Scientific and Practical Psychoneurological Center

Kustov G.V.

Moscow Research and Clinical Centre for Neuropsychiatry

ORCID: 0000-0001-7755-1175

Pashnin E.V.

Scientific and Practical Psychoneurological Center

Gulyaeva N.V.

Scientific and Practical Psychoneurological Center;
Institute of Higher Nervous Activity and Neurophysiology of RAS

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

SPIN RSCI: 7691-3288
Scopus AuthorID: 7003326363
ResearcherID: Y-6725-2018
ORCID: 0000-0002-1170-6127

Received:

10.09.2020

Accepted:

10.09.2020

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