Chondroprotectors (CP) are biological agents that contribute to the regeneration of the cartilage surfaces, joint capsule, participating in the metabolism of the articular cartilage. Progressive loss of hyaline cartilage and a decrease in chondroitin sulfate (CS) is observed in osteoarthritis (OA) including low back pain. OA therapy is aimed at slowing disease progression, relief of pain symptoms, reduction of functional disorders. With this purpose, orally or injectable CP (chondroguard) are used. The optimal dosing regimen for the parenteral forms of CP is recommended: 3 injections of 1 ml (100mg) of chondroguard introduction for 1 week, 2 ml (200mg) from the 4-th injection, 25—30 injections at 200 mg in a day, with a second 6 month course.