Objective. To estimate the character of neurophysiological monitoring in patients with thoracic and lumbar spine injuries at different treatment stages. Material and methods. Thirty-eight patients with non-complicated (22 patients, group 1) and complicated (16 patients, group 2) thoracic and lumbar spine injuries underwent electroneuromyography (ENM) and transcranial magnetic stimulation (TMS). The examination was performed at early (up to 2 weeks) and later (more than 1 month) post-injury periods, before the operation and on the 10th day after decompressing-stabilizing interventions. Results. Before the operation, 71.4% patients of group 1 had ENM-signs of suppressed motor neuron activity in L5 segment of the spinal cord with peroneal nerve axonopathy. The most significant changes in ENM-indexes were observed in medullary channel stenosis of more than 30%. TMS parameters in group 1 were normal while in the 2nd group, EMN and TMS results before the operation demonstrated preserved motor neuron activity at the injury level despite gross neurological symptoms and 100% of medullary channel lumen deficit. In the postoperative period, ENM and TMS revealed no definite negative dynamics in patients of both groups. Patients with locomotor disorders, who underwent surgery at late post-injury periods, showed neurophysiological dynamics on the 10th day postoperatively. Low amplitude motor evoked potentials (kMEP), which were not present before, suggested initial signs of conductibility restoration (in 22% of patients) that proved the effectiveness of decompressive interventions in the long-term post-injury period. Conclusion. ENM- and TMS monitoring in patients with complicated and non-complicated injuries of thoracic and lumbar spine allowed revealing the positive influence of decompressing-stabilizing operations conducted both at early and late post-injury periods on the state of spinal cord conductibility and segmental apparatus.