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Burd S.G.

Kafedra nevrologii i neĭrokhirurgii lechebnogo fakul'teta

Lebedeva A.V.

FGBU "Federal'nyĭ nauchnyĭ tsentr transplantologii i iskusstvennykh organov im. akad. V.I. Shumakova" Minzdrava Rossii, Moskva

Mironov M.B.

kafedra nevrologii i neĭrokhirurgii pediatricheskogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
Tsentr detskoĭ nevrologii i épilepsii, Moskva

Avakian G.G.

Department of Neurology and Neurosurgery of the N.I. Pirogov Russian National Research Medical University

Rubleva Yu.V.

Pirogov Russian National Research Medical University, Moscow

Indication of antiepileptic drugs to patients with epilepsy: results of the survey of neurologists

Authors:

Burd S.G., Lebedeva A.V., Mironov M.B., Avakian G.G., Rubleva Yu.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(5): 36‑38

DOI: 10.17116/jnevro20181185136

Read: 1698 times

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Table of contents

INDICATION OF ANTIEPILEPTIC DRUGS TO PATIENTS WITH EPILEPSY: RESULTS OF THE SURVEY OF NEUROLOGISTS
INDICATION OF ANTIEPILEPTIC DRUGS TO PATIENTS WITH EPILEPSY: RESULTS OF THE SURVEY OF NEUROLOGISTS

To cite this article:

Burd SG, Lebedeva AV, Mironov MB, Avakian GG, Rubleva YuV. Indication of antiepileptic drugs to patients with epilepsy: results of the survey of neurologists. S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(5):36‑38. (In Russ.)
https://doi.org/10.17116/jnevro20181185136

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Objective. To study knowledge and opinions of neurologists about priorities in using antiepileptic drugs (AEP). Material and methods. Eighty-one neurologists from Moscow and surrounding regions were surveyed to identify the factors that influenced the choice of AEP. Results and conclusion. Valproic acid was the most frequently used drug followed by levetiracetam and carbamazepine, which reflected the overall picture of PEP indication in patients with epilepsy in the Russian population. Levetiracetam occupies a leading position as the starting drug for treatment of epilepsy; most often prescribed to women, patients with generalized seizures and idiopathic epilepsy. It is the drug of choice as adjuvant remedies for Duo therapy.

Keywords:

epilepsy
levetiracetam
epiterra long
compliance
bioavailability

Authors:

Burd S.G.

Kafedra nevrologii i neĭrokhirurgii lechebnogo fakul'teta

Lebedeva A.V.

FGBU "Federal'nyĭ nauchnyĭ tsentr transplantologii i iskusstvennykh organov im. akad. V.I. Shumakova" Minzdrava Rossii, Moskva

Mironov M.B.

kafedra nevrologii i neĭrokhirurgii pediatricheskogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
Tsentr detskoĭ nevrologii i épilepsii, Moskva

Avakian G.G.

Department of Neurology and Neurosurgery of the N.I. Pirogov Russian National Research Medical University

Rubleva Yu.V.

Pirogov Russian National Research Medical University, Moscow

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References:

  1. Tantsura L.N., Goranskii Yu.I. Vybor terapii epilepsii u zhenshchin i detei: kak soblyusti balans effektivnosti i bezopasnosti? Materialy XVIII konferentsii Ukrainskoi protivoepilepticheskoi ligi «Epilepsiya i paroksizmal'nye sostoyaniya» 16 maya 2014 g. Zdorov`ya UkraIni; 2014. http://health-ua.com/pics/pdf/ZU_2014_Nevro_3/33.pdf (In Russ.)
  2. Mawhinney E, Craig J, Morrow J, Russell A, Smithson WH, Parsons L, Morrison PJ, Liggan B, Irwin B, Delanty N, Hunt SJ. Levetiracetam in pregnancy: Results from the UK and Ireland epilepsy and pregnancy registers. Neurology. 2013;80:400-405. https://doi.org/10.1212/WNL.0b013e31827f0874
  3. Anderson P. Lamotrigine, Levetiracetam top aeds in pregnancy. American Epilepsy Society (AES) 2016 Annual Meeting. Poster 1.211, December, 2016.
  4. Werhahn KJ, Klimpe S, Balkaya S, Trinka E, Kramer G. The safety and efficacy of add-on levetiracetam in elderly patients with focal epilepsy: A one-year observational study. Seizure. 2011;20(4):305-311. https://doi.org/10.1016/j.seizure.2010.12.015
  5. Toroponina GG. Levetiracetam in treatment of epilepsy, own experience of application in adult patients. Medicinskij sovet. 2017;10:60-64. (In Russ.) https://doi.org/10.21518/2079-701X-2017-10-60-64
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  7. Karlov VA, Vlasov PN, Zhidkova IA. Efficacy of generic levetiracetam (epiterra) in monotherapy for epilepsy in adult patients: Preliminary results. Neurology, Neuropsychiatry, Psychosomatics. 2015;(1):36-40. (In Russ.) https://doi.org/10.14412/2074-2711-2015-1S-36-40
  8. Montouris G, Morris G. Reproductive and sexual dysfunction in men with epilepsy. Epilepsy & Behavior. 2005;7:7-14.
  9. Roste LS, Taubøll E, Haugen T, Bjørnenak T, Saetre E, Gjerstad L. Alterations in semen parameters in men with epilepsy treated with valproate or carbamazepine monotherapy. Eur J Neurol. 2003;10(5):501-506.
  10. Isojärvi J, Löfgren E, Juntunen K, Pakarinen A, Päivänsalo M, Rautakorpi I, Tuomivaara L. Effect of epilepsy and antiepileptic drugs on male reproductive health. Neurology. 2004;62(2):247-253. PMID: 14745062.
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