The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Amelin A.V.

Sankt-Peterburg

Iliukhina A.Iu.

Shmonin A.A.

First Saint-Petersburg Pavlov State Medical University, Saint-Petersburg;
The Northwestern Federal Medical Research Center, Saint-Petersburg;
Saint-Petersburg City Hospital №26, 196247, Saint-Petersburg, Russia

Noopept in the treatment of mild cognitive impairment in patients with stroke

Authors:

Amelin A.V., Iliukhina A.Iu., Shmonin A.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(10): 44‑46

Read: 7956 times

Download PDF (RU)
Contact the author
Table of contents

NOOPEPT IN THE TREATMENT OF MILD COGNITIVE IMPAIRMENT IN PATIENTS WITH STROKE
NOOPEPT IN THE TREATMENT OF MILD COGNITIVE IMPAIRMENT IN PATIENTS WITH STROKE

To cite this article:

Amelin AV, Iliukhina AIu, Shmonin AA. Noopept in the treatment of mild cognitive impairment in patients with stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(10):44‑46. (In Russ.)

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Mediasphera_Net
Close metadata
Recommended articles:
Meta-analysis of randomized controlled trials of the effe­ctiveness of Prospekta in the treatment of vascular cognitive impairment of varying seve­rity. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(6):62-69
Late-onset schi­zophrenia and schi­zophrenia-like psychosis with very late onset. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(7):32-40
Indi­cators of cognitive impairment of varying seve­rity in the acute period of ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8-2):14-20
Repeated ischemic stro­kes due to infe­ctious arte­ritis of both inte­rnal caro­tid and basi­lar arte­ries as a complication of sphe­noiditis and otitis. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8-2):31-37
Cases of successful thro­mbus extraction in ischemic stroke asso­ciated with the new coro­navirus infe­ction COVID-19. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8-2):38-46
On the issue of opti­mizing protein and energy supply for patients with acute cere­brovascular acci­dent. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8-2):51-55
Place of oligopeptide H-Met-Glu-His-Phe-Pro-Gly-Pro-OH in the therapy and reha­bilitation of patients with ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8-2):56-63
Clinical effi­cacy and safety of Pica­milon in patients with progressive chro­nic cere­bral ischemia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8):71-80
The randomized double-blind placebo-controlled study of effi­cacy and safety of mexi­dol in the complex therapy of ischemic stroke in the acute period. S.S. Korsakov Journal of Neurology and Psychiatry. 2006;(12-2):47-54
Asse­ssment of vole­mic status in acute period of ischemic stroke. Russian Journal of Anesthesiology and Reanimatology. 2024;(5):64-71

Noopept is a neuroprotector and nootropics. Literature data revealed the treatment effect of noopept on mild cognitive impairment in patients with discirculatory encephalopathy. The present open prospective study included 60 patients with stroke treated with noopept during 12 months. Cognitive functions were assessed before and after treatment using neuropsychological tests. An analysis of MMSE scores and lateral and categorical associations revealed the significant improvement of cognitive functions after 2 months in patients of the main group compared to the controls. The global assessment of efficacy revealed the mild improvement in the main group while no changes were found in the control group. The results have demonstrated that noopept, used in dose 20mg daily during 2 months, improves cognitive functions in stroke patients and has a high level of safety.

Keywords:

noopept
ischemic stroke
mild cognitive impairment in patients with stroke

Authors:

Amelin A.V.

Sankt-Peterburg

Iliukhina A.Iu.

Shmonin A.A.

First Saint-Petersburg Pavlov State Medical University, Saint-Petersburg;
The Northwestern Federal Medical Research Center, Saint-Petersburg;
Saint-Petersburg City Hospital №26, 196247, Saint-Petersburg, Russia

List of references:

  1. Avedisova A.S., Yastrebov D.V. Sravnitel'naya effektivnost' noopepta i piratsetama pri terapii astenicheskikh rasstroistv i narushenii organicheskogo geneza. Rus med zhurn 2007; 5: 434-437.
  2. Zakharov V.V., Yakhno N.N. Narusheniya pamyati. M: GeotarMed 2003; 150.
  3. Neznamov G.G., Teleshova E.S. Rezul'taty sravnitel'nogo izucheniya noopepta i piratsetama pri lechenii bol'nykh s legkimi kognitivnymi narusheniyami pri organicheskikh zabolevaniyakh golovnogo mozga sosudistogo i travmaticheskogo geneza. Zhurn nevrol i psikhiat 2008; 108: 3: 33-42.
  4. Testy, shkaly oprosniki. V pomoshch' praktikuyushchemu vrachu. M 2006.
  5. Yakhno N.N., Zakharov V.V. Sosudistye kognitivnye rasstroistva. Rus med zhurn 2005; 13: 12: 789-793.
  6. Yakhno N.N. Kognitivnye rasstroistva v nevrologicheskoi praktike. Nevrol zhurn 2006; Prilozhenie 1: 4-12.
  7. Yakhno N.N., Suslina Z.A., Gribacheva I.A. i dr. Vliyanie preparata bilobil forte na umerennye kognitivnye narusheniya u patsientov s distsirkulyatornoi entsefalopatiei I-II stadii: kliniko-neiropsikhologicheskoe issledovanie. Rus med zhurn 2008; 16: 12: 1626-1629.
  8. Cerebrovascular disease, cognitive impairment and dementia. Second edition of Cerebrovascular disease and dementia. Edited by J. O'Brien, D. Ames, L. Gustafson et al. Martin Dunitz 2004.
  9. DiCarlo A., Baldereschi M., Amaducci L. et al. Cognitive impairment without dementia in older people: prevalence, vascular risk factors, impact on disability. The Italian Longitudinal Study on Aging. J Am Ger Soc 2000; 48: 775-782.
  10. ECDEU Assessment Manual for Psychopharmacology. Edited by W. Guy. 1976. Rockville, MD, U.S. Department of Health, Education, and Welfare.
  11. Graham J.E., Rockwood K., Beattie E.L. et al. Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet 1997; 349: 1793-1796.
  12. Hachinski V., Bowler J.V. Vascular dementia: diagnostic criteria for research studies. Neurology 1993; 43: 2159-2160.
  13. Lovenstone S., Gauthier S. Management of dementia. London: Martin Dunitz 2001.
  14. Rockwood K., Wentzel C, Hachinski V. et al. Prevalence and outcomes of vascular cognitive impairment. Neurology 2000; 54: 447-451.
  15. Zigmond A.S., Snaith R.P. The hospital anxiety and depression scale. Acta Psychiat Scand 1983; 67: 6: 361-370.

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.