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Skvortsova V.I.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet;
NII tserebrovaskuliarnoĭ patologii i insul'ta, Moskva

Petrova E.A.

FGBU "NII onkologii im. N.N. Petrova" Minzdrava Rossii, Sankt-Peterburg

Brusov O.S.

Scientific center of mental health, Moscow, Russia

Savina M.A.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Shaklunova N.V.

Kafedra fundamental'noĭ, klinicheskoĭ nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, NII tserebrovaskuliarnoĭ patologii i insul'ta Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Klyushnik T.P.

Scientific center of mental health, Moscow, Russia

Georgievskaia N.A.

Kafedra fundamental'noĭ, klinicheskoĭ nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, NII tserebrovaskuliarnoĭ patologii i insul'ta Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Faktor M.I.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Pathogenetic characteristics of post stroke affective disorders

Authors:

Skvortsova V.I., Petrova E.A., Brusov O.S., Savina M.A., Shaklunova N.V., Klyushnik T.P., Georgievskaia N.A., Faktor M.I.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(7): 35‑40

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To cite this article:

Skvortsova VI, Petrova EA, Brusov OS, et al. . Pathogenetic characteristics of post stroke affective disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(7):35‑40. (In Russ.)

 
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Fifty patients with affective disorders developed after first cerebral stroke were studied. A spectrum of affective disorders included post-stroke depressions, generalized anxiety disorders, anxiety-depressive disorders and pseudo post-stroke depressions. Platelet serotonin (PS) levels were measured in these patients as well. The levels of PS at the first three days after stroke and their changes towards the 28th day are associated with the development of post-stroke affective disorders. The development of anxiety-depressive disorders in the acute period of stroke is related to the localization of brain lesion focus. The low levels of PS in patients at the first three days after stroke may be the risk factor of delayed affective disorders development.

Keywords:

stroke
post-apoplectic affective disorders
platelet serotonin
serum α1 proteinase inhibitor

Authors:

Skvortsova V.I.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet;
NII tserebrovaskuliarnoĭ patologii i insul'ta, Moskva

Petrova E.A.

FGBU "NII onkologii im. N.N. Petrova" Minzdrava Rossii, Sankt-Peterburg

Brusov O.S.

Scientific center of mental health, Moscow, Russia

Savina M.A.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Shaklunova N.V.

Kafedra fundamental'noĭ, klinicheskoĭ nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, NII tserebrovaskuliarnoĭ patologii i insul'ta Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Klyushnik T.P.

Scientific center of mental health, Moscow, Russia

Georgievskaia N.A.

Kafedra fundamental'noĭ, klinicheskoĭ nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, NII tserebrovaskuliarnoĭ patologii i insul'ta Nauchnogo tsentra psikhicheskogo zdorov'ia RAMN, Moskva

Faktor M.I.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

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