Comparative effectiveness of mood stabilizers in the complex therapy of bulimia nervosa

The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Search result: 0

Marilov V.V.

Kafedra psikhiatrii i meditsinskoĭ psikhologii Rossiĭskogo universiteta druzhby narodov, Moskva

Sologub M.B.

Spetsializirovannaia klinicheskaia bol'nitsa #8 im. Z.P. Solov'eva, «Klinika nevrozov»

Comparative effectiveness of mood stabilizers in the complex therapy of bulimia nervosa

Authors:

Marilov V.V., Sologub M.B.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(1): 59‑61

Views: 19046

Downloaded: 315

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Marilov VV, Sologub MB. Comparative effectiveness of mood stabilizers in the complex therapy of bulimia nervosa. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(1):59‑61. (In Russ.)

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)

Close metadata

Forty-five patients with bulimia nervosa were treated with the antidepressant fluoxetine and additionally with mood-stabilizers: 25 patients received carbamazepine and 20 patients - lamotrigine. A clinical follow-up and experimental-psychological study was conducted before the therapy, after 30 days and after 1 year. The use of fluoxetine in the combination with mood-stabilizers allowed to achieve the marked and stable improvement of the patient's state. Lamotrigine compared to carbamazepine reduced the depression level and improved cognitive functions. After one year, the better social rehabilitation was seen in the group treated with lamotrigine (64,7%) compared to carbamazepine (34,8%). The preventive therapy with lamotrigine was more effective than that with carbamazepine: 35,2% and 46,1%, of patients respectively, relapsed after the withdrawal of fluoxetine.

Keywords:

bulimia nervosa

treatment

antidepressants

mood stabilizers

Authors:

Marilov V.V.

Kafedra psikhiatrii i meditsinskoĭ psikhologii Rossiĭskogo universiteta druzhby narodov, Moskva

Sologub M.B.

Spetsializirovannaia klinicheskaia bol'nitsa #8 im. Z.P. Solov'eva, «Klinika nevrozov»

List of references:

Vovin R.Ya., Digilov A.G., Skorik A.I. Profilakticheskoe lechenie affektivnykh psikhozov finlepsinom. Zhurn nevropatol i psikhiat 1984; 8: 1226-1230.
Marilov V.V., Sologub M.B. Dinamika bulimicheskikh rasstroistv pri nervnoi anoreksii i nervnoi bulimii. Zhurn nevrol i psikhiat 2008; 101: 1: 18-22.
Bowden C.L., Calabrese J.R., Sachs G. et al. A randomized, placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. In: Scientific Abstracts of the 40th Annual Meeting of the American College of Neuropsychopharmacology (9-13 December, 2001). Waikoloa 2001; 238.
Bowden C.L., Ghaemi N., Gyulai L. et al. Lamotrigine delays mood episodes in recently depressed bipolar I patients. In: New Research Abstracts of the 155th Annual Meeting of the American Psychiatric Association (18-23 May, 2002). Philadelphia 2002; 81.
Calabrese J.R., Suppes T., Bowden C.L. et al. A double-blind, placebo-controlled prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. J Clin Psychiat 2000; 61: 841-850.
Geddes J.R., Calabrese J.R., Goodwin G.M. Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials. Br J Psychiat 2009; 194: 1: 4-9.
Grilo S.M., Jackson T.D., Masheb R.M. Teasing history and eating disorder features: an age- and body mass index-matched comparison of bulimia nervosa and binge-eating disorder. Compr Psychiat 2002; 43: 2: 108-113.
Hsu L.K.G. Epidemiology of the eating disorders. Psychiat Clin North Am 1996; 19: 4: 681-700.
Keel et al. Long-term Outcome of Bulimia Nervosa. Arch Gen Psychiat 1999; 56: 63-69.
Kravitz H.M., Fawcett J. Carbamazepine in the treatment of affective disorders. Med Sci Res 1987; 15: 1-8.
Patton G.C., Selzer R., Coffey C. et al. Onset of adolescent eating disorders: population based cohort study over 3 years. BMJ 1999; 318: 7186: 765-768.
Stromgren L., Boller S. Carbamazepine in treatment and prophylaxis of manic-depressive disorder. Psychiat Dev 1985; 4: 349-367.

Close metadata

Log in to the site using your account in one of the services

Registration

Last Name

Name

Middle Name

E-mail

Phone

Address

Country

Zip

City

Region

Street

Home

Apartmen

Legal entity name

ИНН

КПП

Password

Password

Repeat password

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.