Reversible cerebral vasoconstriction syndrome and ischemic stroke

Close metadata

Recommended articles:

New data on the pathophysiology of ischemic stroke: epigenetic mechanisms in focus. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(12-2):24-29

Craniocerebral hypothermia in the acute period of ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(12-2):43-48

The impact of therapy with Mexidol on neurological deficit and functional outcome in patients with ischemic stroke: a systematic review and meta-analysis. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(12-2):49-60

The effect of rehabilitation with sensory glove and virtual reality on concentration of brain-derived neurotrophic factor and event related potential P300 in the early rehabilitation period after ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(12-2):75-81

An effect of ethylmethylhydroxypyridine succinate and ethylmethylhydroxypyridine malate on changes in mitochondrial function under conditions of focal cerebral ischemia. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(11):111-116

Bullet embolism of internal carotid artery. (A case report and literature review). Burdenko's Journal of Neurosurgery. 2023;(6):85-92

Efficacy and safety of surgical treatment of patients with pathological tortuosity of the internal carotid artery. Pirogov Russian Journal of Surgery. 2024;(1):64-70

Functional transcranial dopplerography is a diagnostic tool for cognitive impairment syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(2):7-12

Advisability of carotid endarterectomy in asymptomatic patients. Pirogov Russian Journal of Surgery. 2024;(3):45-53

The article describes a 45-year-old female patient with recurrent transient ischemic attacks and ischemic stroke due to spontaneous spasm of the middle cerebral artery, the anterior cerebral artery and distal part of the internal cerebral artery on the left, verified by MR angiography and CT angiography. It is assumed that the spasm caused damage to the vascular wall, an increase in its permeability, the development of edema, inflammation and subsequent fibrosis, therefore a complete restoration of the arterial lumen did not occur.

Keywords:

reversible cerebral vasoconstriction

ischemic stroke

transient ischemic attacks

MR-angiography

CT-angiography

high-resolution vascular wall imaging

Authors:

Kalashnikova L.A.

Research Center of Neurology

ORCID: 0000-0003-1142-0548

Konovalov R.N.

Research Center of Neurology

ORCID: 0000-0001-5539-245X

Dobrynina L.A.

Research Center of Neurology

ORCID: 0000-0001-9929-2725

Received:

12.09.2023

Accepted:

14.09.2023

List of references:

Calabrese LH, Dodick DW, Schwedt TJ, et al. Narrative review: reversible cerebral vasoconstriction syndromes. Ann Intern Med. 2007;146(1):34-44. https://doi.org/10.7326/0003-4819-146-1-200701020-00007
Ducros A, Boukobza M, Porcher R, et al. The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome. A prospective series of 67 patients. Brain. 2007;130(Pt 12):3091-3101. https://doi.org/10.1093/brain/awm256
Singhal AB, Hajj-Ali RA, Topcuoglu MA, et al. Reversible cerebral vasoconstriction syndromes: analysis of 139 cases. Arch Neurol. 2011;68(8):1005-1012. https://doi.org/10.1001/archneurol.2011.68
Wolff V, Ducros A. Reversible Cerebral Vasoconstriction Syndrome Without Typical Thunderclap Headache. Headache. 2016;56:674-687. https://doi.org/10.1111/head.12794
Chen S-P, Wang S-J. Pathophysiology of reversible cerebral vasoconstriction syndrome Biomed Sci. 2022;29(1):72. https://doi.org/10.1186/s12929-022-00857-4
Sergeev AV, Osipova VV, Tabeeva GR, Snopkova EV. Reversible cerebral vasoconstriction syndrome. Neurological Journal. 2012;(3):4-11.
Kalashnikova LA. Reversible Cerebral Vasoconstriction Syndrome and Its Complications. Human Physiology. 2022;48(8):1-10. https://doi.org/10.1134/S036211972208014X
Klocheva EG, Goldobin VV. Diagnosis of reversible central vasoconstriction syndrome: clinical manifestations and data of methods of radiation diagnostics Radiation diagnostics and therapy. 2018;3(9):50-55. (In Russ.). https://doi.org/10.22328/2079-5343-2018-9-3-50-55
Chen S-P, Jong-Ling Fuh, Shuu-Jiun Wang. Reversible cerebral vasoconstriction syndrome: an under-recognized clinical emergency. Therapeutic Advances in Neurological Disorders. 2010;3:161-167. https://doi.org/10.1177/1756285610361795
Patel SD, Topiwala K, Oliver FO, et al. Outcomes Among Patients With Reversible Cerebral Vasoconstriction Syndrome: A Nationwide United States Analysis Stroke. Stroke. 2021;52(12):3970-3977. https://doi.org/10.1161/STROKEAHA.121.034424
Magid-Bernstein J, Omran SS, Parikh NS, et al. RCVS: Symptoms, Incidence, and Resource Utilization in a Population-Based US Cohort. Neurology. 2021;97(3):e248-e253. https://doi.org/10.1212/WNL.0000000000012223
Caria F, Zedde M, Gamba M, et al. Italian Project on Stroke at Young Age (IPSYS) Investigators. The clinical spectrum of reversible cerebral vasoconstriction syndrome: The Italian Project on Stroke at Young Age (IPSYS). Cephalalgia. 2019;39(10):1267-1276. https://doi.org/10.1177/0333102419849013
Choi HA, Lee MJ, Chung C-S. Cerebral endothelial dysfunction in reversible cerebral vasoconstriction syndrome: a case-control study. J Headache Pain. 2017;18(1):29. https://doi.org/10.1186/s10194-017-0738-x
Lee MJ, Cha J, Choi HA, et al. Blood-brain barrier breakdown in reversible cerebral vasoconstriction syndrome: Implications for pathophysiology and diagnosis. Ann Neurol. 2017;81(3):454-466. https://doi.org/10.1002/ana.24891
Ducros A. Reversible cerebral vasoconstriction syndrome. Lancet Neurol. 2012;11:906-917. https://doi.org/10.1016/S1474-4422(12)70135-7
Choi HA, Lee MJ, Choi H, Chung S-C. Characteristics and demographics of reversible cerebral vasoconstriction syndrome: A large prospective series of Korean patients. Cephalalgia. 2018;38:765-775. https://doi.org/10.1177/0333102417715223
Xing B, Lenck S, Krings T, et al. Angiographic Characteristics of Hemorrhagic and Ischemic Phases of Reversible Cerebral Vasoconstriction Syndrome. Clin Neuroradiol. 2020;30(1):85-89. Epub 2018 Nov 2. https://doi.org/10.1007/s00062-018-0736-7
Garg A, Starr M, Rocha M, Ortega-Gutierrez S. Predictors and outcomes of ischemic stroke in reversible cerebral vasoconstriction syndrome. J Neurol. 2021;268(8):3020-3025. https://doi.org/10.1007/s00415-021-10456-2
Hamel E. Perivascular nerves and the regulation of cerebrovascular tone. J Appl Physiol (1985). 2006;100(3):1059-1064.
Topcuoglu MA, Singhal AB. Hemorrhagic Reversible Cerebral Vasoconstriction Syndrome Features and Mechanisms. Stroke. 2016;47:23-29. https://doi.org/10.1161/STROKEAHA.116.013136
Chen CY, Chen SP, Fuh JL, et al. Vascular wall imaging in reversible cerebral vasoconstriction syndrome — a 3-T contrast-enhanced MRI study. J Headache Pain. 2018;19(1):74. https://doi.org/10.1186/s10194-018-0906-7
Kalashnikova LA, Dobrynina LA, Legenko MS. Primary vasculitis of the central nervous system. Journal of Neurology and Psychiatry named after S.S.Korsakov. 2019;119(8):112-123. (In Russ.). https://doi.org/10.17116/jnevro2019119081113
de Boysson H, Parienti JJ, Mawet J, et al. Primary angiitis of the CNS and reversible cerebral vasoconstriction syndrome: A comparative study. Neurology. 2018;91(16):e1468-e1478. https://doi.org/10.1212/WNL.0000000000006367
Kunchok A, Castley HC, Aldous L, et al. Fatal reversible cerebral vasoconstriction syndrome. J Neurol Sci. 2018;385:146-150. Epub 2017 Dec 8. https://doi.org/10.1016/j.jns.2017.12.009
Burton TM, Bushnell CD. Reversible Cerebral Vasoconstriction Syndrome. Stroke. 2019;50(8):2253-2258. https://doi.org/10.1161/STROKEAHA.119.024416

Close metadata